117125-07-2Relevant articles and documents
Unaromatized Tetrahydrobenzimidazole Synthesis from p-Benzoquinone and N-Arylamidines and their Cytotoxic Potential
Tran, Minh Quan,Nguyen, Thanh Binh,Sawadogo, Wamtinga Richard,Ermolenko, Ludmila,Song, Sungmi,Retailleau, Pascal,Diederich, Marc,Al-Mourabit, Ali
, p. 5878 - 5884 (2018/10/09)
A diverse set of unaromatized and densely functionalized tetrahydrobenzimidazole adducts were obtained in good yields by simple mixing p-benzoquinone 1 with N-arylamidines 2 under mild conditions. The main features of these adducts include a hemi N,O-acet
New Benzimidazole Synthesis
Benincori, T.,Sannicolo, F.
, p. 1029 - 1033 (2007/10/02)
Thermal or acid catalyzed cyclization of several N-(N-arylbenzimidoyl)-1,4-benzoquinoneimines 2 affords 1-aryl-6-hydroxy-2-phenylbenzimidazoles 3 in fairly good yields.Structural proofs and kinetic support for the reaction mechanism are given.