1173294-90-0

Basic information

• Product Name: (2-(pyridin-2’-yl)phenyl)(p-tolyl)methanone
• Synonyms: (2-(pyridin-2’-yl)phenyl)(p-tolyl)methanone
• CAS NO: 1173294-90-0
• Molecular Weight: 273.334
• Mol File: 1173294-90-0.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: (2-(pyridin-2’-yl)phenyl)(p-tolyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-(pyridin-2’-yl)phenyl)(p-tolyl)methanone(1173294-90-0)
• EPA Substance Registry System: (2-(pyridin-2’-yl)phenyl)(p-tolyl)methanone(1173294-90-0)

Safety Data

• Hazardous Substances Data: 1173294-90-0(Hazardous Substances Data)

Upstream product

• 1008-89-5 2-phenylpyridine 
• 5400-87-3 1-p-tolyl-propane-1,2-dione-2-oxime 
• 5337-93-9 4'-methylpropiophenone 
• 698-00-0 2-bromo-N,N-dimethylaniline 
• 1221640-33-0 N,N-dimethyl-2-(pyridin-2-yl)aniline 
• 201230-82-2 carbon monoxide 
• 380481-66-3 5,5-dimethyl-2-(4-methylphenyl)-1,3,2-dioxaborinane 
• 1075-47-4 4-methylphenylglyoxal 
• 766-97-2 4-n-methylphenylacetylene 
• 104-85-8 para-methylbenzonitrile 
• 13227-01-5 2-amino-2-(4-methylphenyl)acetic acid 
• 104-81-4 4-Methylbenzyl bromide 
• 104-82-5 4-Methylbenzyl chloride 
• 18584-20-8 4-methylmandelic acid 

Relevant articles and documents

A Strategy for Amide C-N Bond Activation with Ruthenium Catalyst: Selective Aromatic Acylation

A strategy for amide C-N bond activation with ruthenium catalyst is described for the first time. The in situ formed bis-cycloruthenated complexes were demonstrated to be the key active species with superior oxidative addition ability to an inert amide C-N bond. The direct C-H bond activation of 2-arylpyridines followed by the amide C-N bond activation took place in the presence of a ruthenium precatalyst to produce monoacylation products in moderate to good yields. Synthetically useful functional groups, such as halogen atoms (F and Cl), ester, acetyl, and vinyl, remained intact during tandem C-H/C-N bond activation reactions.

Silver catalyzed pyridine-directed acceptorless dehydrogenation of secondary alcohols

A silver catalyzed pyridine-directed acceptorless dehydrogenation of secondary benzyl alcohols was developed. This general procedure delivers ketones with high atom-economy and hydrogen was the sole byproduct. This dehydrogenation reaction has a good functional group tolerance and high efficiency (up to 90% yield and 10,000/1 substrates-to-catalyst ratio).

Dual photoredox/palladium-catalyzed C-H acylation of 2-arylpyridines with oxime esters

An unprecedented dual photoredox/palladium-catalyzed iminyl-radical-mediated C-C bond cleavage and directed ortho C-H acylation of 2-arylpyridines by using oxime esters is described. Oxime esters can serve as efficient acyl sources through formation of the corresponding acyl radicals by photoredox-catalyzed iminyl-radical-mediated C-C bond cleavage. This redox-neutral protocol features excellent regioselectivity, a broad substrate scope, and good functional-group tolerance with respect to both components, giving a broad range of aryl ketones with generally good yields.