1173977-35-9

Basic information

• Product Name: N-(4-chlorophenyl)-3-methoxy-benzenesulfonamide
• Synonyms: N-(4-chlorophenyl)-3-methoxy-benzenesulfonamide
• CAS NO: 1173977-35-9
• Molecular Weight: 297.762
• Mol File: 1173977-35-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-chlorophenyl)-3-methoxy-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorophenyl)-3-methoxy-benzenesulfonamide(1173977-35-9)
• EPA Substance Registry System: N-(4-chlorophenyl)-3-methoxy-benzenesulfonamide(1173977-35-9)

Safety Data

• Hazardous Substances Data: 1173977-35-9(Hazardous Substances Data)

Upstream product

• 10130-74-2 m-Methoxybenzenesulfonyl chloride 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 1531587-74-2 C₂₃H₂₀ClN₃O₅S 
• 1082398-63-7 C₁₂H₁₀ClNO₃S 
• 1173977-36-0 [(4-Chlorophenyl)-(3-methoxy-benzenesulphonyl)-amino]-acetic acid methyl ester 

Relevant articles and documents

Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c] pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists

The discovery and optimization of novel N-(3-(1,3-dioxo-2,3-dihydro-1H- pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamide GPR119 agonists is described. Modification of the pyridylphthalimide motif of the molecule with R1 =-Me and R2 =-iPr substituents, incorporated with a 6-fluoro substitution on the central phenyl ring offered a potent and metabolically stable tool compound 22.

BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS

There is provided compounds of formula I, wherein ring A, D1, D2a, D2b, D3, L1, Y1, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.