1174146-50-9Relevant articles and documents
Ruthenium-Catalyzed Hydrogen Evolution o-Aminoalkylation of Phenols with Cyclic Amines
Cao, Liang,Zhao, He,Tan, Zhenda,Guan, Rongqing,Jiang, Huanfeng,Zhang, Min
, p. 4781 - 4785 (2020)
Herein, we present a ruthenium-catalyzed new hydrogen evolution ortho-aminoalkylation of phenolic derivatives with cyclic amines as the coupling agents. The developed cross-coupling reaction offers a practical platform for direct access to a variety of functionalized phenols with the features of good substrate and functional group compatibility, readily available catalyst system and feedstocks, no need for additional sacrificial oxidants, and high atom efficiency.
Redox-neutral α,β-difunctionalization of cyclic amines
Chen, Weijie,Kang, Youngku,Wilde, Richard G.,Seidel, Daniel
, p. 5179 - 5182 (2014/05/20)
In contrast to the continuously growing number of methods that allow for the efficient α-functionalization of amines, few strategies exist that enable the direct functionalization of amines in the β-position. A general redox-neutral strategy is outlined for amine β-functionalization and α,β-difunctionalization that utilizes enamines generated insitu. This concept is demonstrated in the context of preparing polycyclic N,O-acetals from simple 1-(aminomethyl)-β-naphthols and 2-(aminomethyl)-phenols. An unprecedented α,β-difunctionalization reaction of amines affords polycyclic N,O-acetals from simple 1-(aminomethyl)-β-naphthols or 2-(aminomethyl)-phenols. These transformations are redox-neutral and proceed in the absence of any additives.
A novel iron-catalyzed decarboxylative Csp3 - Csp2 coupling of proline derivatives and naphthol
Bi, Hai-Peng,Chen, Wen-Wen,Liang, Yong-Min,Li, Chao-Jun
supporting information; experimental part, p. 3246 - 3249 (2009/12/01)
A novel iron-catalyzed intermolecular decarboxylative Csp3 - Csp2 coupling reaction using proline derivatives as starting materials is developed. In this process, a series of potentially useful ligands (tertiary aminonaphthol) for ca
