1174231-77-6Relevant articles and documents
Synthesis of fully substituted pyrazoles via regio- and chemoselective metalations
Despotopoulou, Christina,Klier, Lydia,Knochel, Paul
, p. 3326 - 3329 (2009)
The full functionalization of the pyrazole ring was achieved by successive regioselective metalations using TMPMgCI-LiCI and TMP2Mg.2LiCI. Trapping with various electrophiles led to trisubstituted pyrazoles. An application to the synthesis of the acaricide Tebufenpyrad is reported.