117444-30-1 Usage
General Description
(3R)-3,4-Dihydro-5-methoxy-2H-1-Benzopyran-3-amine, also known as apomorphine, is a chemical compound used in medicine for the treatment of Parkinson's disease. It functions as a dopamine agonist, which means it activates dopamine receptors in the brain and helps to alleviate symptoms of the disease such as tremors, stiffness, and slow movement. Apomorphine is also used to treat erectile dysfunction in men and is sometimes used in the management of other conditions such as restless legs syndrome. It works by stimulating dopamine receptors in the brain, leading to increased dopamine activity and improved motor function.
Check Digit Verification of cas no
The CAS Registry Mumber 117444-30-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,4,4 and 4 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 117444-30:
(8*1)+(7*1)+(6*7)+(5*4)+(4*4)+(3*4)+(2*3)+(1*0)=111
111 % 10 = 1
So 117444-30-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO2/c1-12-9-3-2-4-10-8(9)5-7(11)6-13-10/h2-4,7H,5-6,11H2,1H3/t7-/m1/s1
117444-30-1Relevant articles and documents
Advances toward new antidepressants with dual serotonin transporter and 5-HT1A receptor affinity within a class of 3-aminochroman derivatives. Part 2
Hatzenbuhler, Nicole T.,Baudy, Reinhardt,Evrard, Deborah A.,Failli, Amedeo,Harrison, Boyd L.,Lenicek, Steven,Mewshaw, Richard E.,Saab, Annmarie,Shah, Uresh,Sze, Jean,Zhang, Minsheng,Zhou, Dahui,Chlenov, Michael,Kagan, Michael,Golembieski, Jeannette,Hornby, Geoffrey,Lai, Margaret,Smith, Deborah L.,Sullivan, Kelly M.,Schechter, Lee E.,Andree, Terrance H.
scheme or table, p. 6980 - 7004 (2009/11/30)
Novel compounds combining a 5-HT1A moiety (3-aminochroman scaffold) and a 5-HT transporter (indole analogues) linked through a common basic nitrogen via an alkyl chain attached at the 1- or 3-position of the indole were evaluated for dual affin