1174520-14-9

Basic information

• Product Name: C₁₄H₁₉N₅O₁₀S
• CAS NO: 1174520-14-9
• Molecular Weight: 449.398
• Mol File: 1174520-14-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₉N₅O₁₀S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₉N₅O₁₀S(1174520-14-9)
• EPA Substance Registry System: C₁₄H₁₉N₅O₁₀S(1174520-14-9)

Safety Data

• Hazardous Substances Data: 1174520-14-9(Hazardous Substances Data)

Upstream product

• 132679-61-9 N^α-(2,4-dinitro-5-fluorophenyl)-L-valinamide 
• 1374772-61-8 baringolin 

Relevant articles and documents

JBIR-78 and JBIR-95: Phenylacetylated peptides isolated from Kibdelosporangium sp. AK-AA56

The search for metabolites of Kibdelosporangium sp. AK-AA56 resulted in the discovery of novel N-phenylacetylated peptides, JBIR-78 (1) and JBIR-95 (2). Compounds 1 and 2 were established to be N-phenylacetylated heptapeptides by extensive NMR and HRESIMS analyses. The absolute configuration of the standard amino acids including a cysteic acid moiety was determined using Marfey's method on the acid hydrolysates of 1 and 2. The relative and absolute configurations of a nonstandard amino acid, β-hydroxyleucine, were elucidated using the J-based and modified Mosher's methods, respectively. In an antimicrobial test, 1 showed antibacterial activity against Micrococcus luteus.

Kocurin, the true structure of PM181104, an anti-methicillin-resistant Staphylococcus aureus (MRSA) thiazolyl peptide from the marine-derived bacterium Kocuria palustris

A new thiazolyl peptide, kocurin (1), was isolated from culture broths of a marine-derived Kocuria palustris. Its structural elucidation was accomplished using a combination of spectroscopic and chemical methods, including HRMS, extensive 1D and 2D NMR analysis, MS/MS fragmentation, and chemical degradation and Marfey's analysis of the resulting amino acid residues. The structure herein reported corrects that previously assigned to PM181104 (3). Kocurin displayed activity against methicillin-resistant Staphylococcus aureus (MRSA), with MIC values in the submicromolar range.