1174524-50-5 Usage
Description
(S)-1-(2,5-dioxoazolidinyloxycarbonyloxy)-2-methylpropyl 2-methylpropanate is a complex ester compound derived from the reaction between (S)-1-(2,5-dioxoazolidinyloxycarbonyloxy)-2-methylpropyl alcohol and 2-methylpropanoic acid. It features a unique molecular structure and specific stereochemistry, which makes it a valuable building block in the synthesis of various chemical compounds, including pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
(S)-1-(2,5-dioxoazolidinyloxycarbonyloxy)-2-methylpropyl 2-methylpropanate is used as a reactant or intermediate for the production of pharmaceuticals due to its unique structure and reactivity. It plays a crucial role in the synthesis of chiral compounds, which are essential in the development of many drugs.
Used in Agrochemical Industry:
In the agrochemical industry, (S)-1-(2,5-dioxoazolidinyloxycarbonyloxy)-2-methylpropyl 2-methylpropanate is utilized as a key component in the synthesis of various agrochemicals. Its versatility as a building block allows for the creation of a wide range of products used in agriculture.
Used in Organic Synthesis:
(S)-1-(2,5-dioxoazolidinyloxycarbonyloxy)-2-methylpropyl 2-methylpropanate is also employed in organic synthesis as a versatile building block for the production of other organic compounds. Its specific stereochemistry makes it an important tool in the development of new and innovative chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 1174524-50-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,4,5,2 and 4 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1174524-50:
(9*1)+(8*1)+(7*7)+(6*4)+(5*5)+(4*2)+(3*4)+(2*5)+(1*0)=145
145 % 10 = 5
So 1174524-50-5 is a valid CAS Registry Number.
1174524-50-5Relevant articles and documents
Process Development toward a Pro-Drug of R-Baclofen
Allsop, Glyn L.,Carey, John S.,Joshi, Sudhir,Leong, Paul,Mirata, Marco A.
, p. 136 - 147 (2021)
This paper describes the process development conducted toward the multi-kilogram synthesis of a novel transported pro-drug of R-baclofen. The key steps in the synthesis were the enzyme-catalyzed kinetic resolution of isopropyl(methylthiocarbonyloxy)methyl-2-methylpropionate using Candida antarctica lipase A to provide the desired (S)-enantiomer. This was followed by the reaction with sulfuryl chloride and N-hydroxysuccinimide to produce (S) 1-(2,5-dioxoazolidinyloxycarbonyloxy)-2-methylpropyl 2-methylpropanate. The synthesis of (S) 1-(2,5-dioxoazolidinyloxycarbonyloxy)-2-methylpropyl 2-methylpropanate enabled the efficient use of R-baclofen in the final coupling stage of the synthesis. The new route reported here is more efficient and sustainable than those reported previously and had the potential to become the commercial route of manufacture.
