1174637-69-4Relevant articles and documents
Chiral cyclic zwitterionic bipyridinium-4-olates for the diastereoselective synthesis of (R,S)- A nd (S,R)-trozamicol
López-González, Ricardo,Zárate, Araceli,Aparicio, David M.,Mendoza, Angel,Gnecco, Dino,Juárez, Jorge R.,Romero-Ceronio, Nancy,Orea, Laura,Terán, Joel L.
, p. 1683 - 1686 (2016/04/04)
A series of new chiral enantiopure cyclic zwitterionic bipyridinium-4-olates compounds were prepared in four steps starting from the corresponding primary chiral amine. With these intermediates, a convenient methodology has been developed for the synthesis of cis-3-piperidinyl-4-hydroxypiperidines. Specifically, the utility of this chiral zwitterionic type intermediate has been demonstrated by the synthesis of (R,S)- A nd (S,R)-trozamicol.