1174913-80-4

Basic information

• Product Name: (R)-2-Aminomethyl-4-boc-morpholine
• Synonyms: (R)-2-(Aminomethyl)morpholine-4-carboxylic acid tert-butyl ester;4-Morpholinecarboxylic acid, 2-(aMinoMethyl)-, 1,1-diMethylethyl ester, (2R)-;(R)-tert-butyl 2-aMinoMethylMorpholine-4-carboxylate;tert-butyl (2R)-2-(aminomethyl)morpholine-4-carboxylate;(R)-2-Aminomethyl-4-boc-morpholine;(R)-4-Boc-2-aminomethylmorpholine
• CAS NO: 1174913-80-4
• Molecular Formula: C₁₀H₂₀N₂O₃
• Molecular Weight: 216.2774
• Mol File: 1174913-80-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 311℃
• Flash Point: 142℃
• Appearance: /
• Density: 1.078
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.37±0.29(Predicted)
• CAS DataBase Reference: (R)-2-Aminomethyl-4-boc-morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Aminomethyl-4-boc-morpholine(1174913-80-4)
• EPA Substance Registry System: (R)-2-Aminomethyl-4-boc-morpholine(1174913-80-4)

Safety Data

• Hazardous Substances Data: 1174913-80-4(Hazardous Substances Data)

Usage

General Description

(R)-2-Aminomethyl-4-boc-morpholine is a chemical compound with the molecular formula C9H18N2O3. It is an amino-protecting reagent used in organic synthesis to protect amino groups from unwanted reactions. The "boc" in its name stands for tert-butyloxycarbonyl, which is a protecting group frequently used in organic chemistry. (R)-2-Aminomethyl-4-boc-morpholine is frequently utilized in the preparation of peptide and nucleotide derivatives. It is also used in the production of pharmaceuticals and as an intermediate in organic synthesis. Additionally, it is known for its low toxicity and ease of handling, making it a popular choice for amino-protection in various chemical reactions.

InChI:InChI=1S/C10H20N2O3/c1-10(2,3)15-9(13)12-4-5-14-8(6-11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1

Upstream product

• 1132683-15-8 tert-butyl (2S)-2-(azidomethyl)morpholine-4-carboxylate 
• 135065-76-8 tert-butyl (2S)-2-(hydroxymethyl)morpholine-4-carboxylate 
• 606139-90-6 tert-butyl (2S)-2-{[(methylsulfonyl)oxy]methyl}morpholine-4-carboxylate 
• 1308849-93-5 (R)-tert-butyl 2-((1,3-dioxoisoindolin-2-yl)methyl)morpholine-4-carboxylate 
• 148638-76-0 tert-butyl (2S)-2-({[(4-methylphenyl)sulfonyl]oxy}methyl)morpholine-4-carboxylate 
• 52520-62-4 (2S)-4-benzyl-2-<<(p-tolylsulfonyl)oxy>methyl>morpholine 
• 132073-82-6 (S)-4-Benzyl-2-(hydroxymethyl)morpholine 

Downstream Products

• 1174913-72-4 tert-butyl (R)-2-((benzyloxycarbonylamino)methyl)morpholine-4-carboxylate 
• 1308849-94-6 (R)-methyl 2-((2-(2,6-difluoro-4-(methylcarbamoyl)phenyl)-5-methyl-1H-benzo[d]imidazol-1-yl)methyl)morpholine-4-carboxylate 
• 1308849-95-7 (R)-tert-butyl 2-((2-amino-4-methylphenylamino)methyl)morpholine-4-carboxylate 
• 1308849-96-8 (R)-4-(1-((4-(tert-butoxycarbonyl)morpholin-2-yl)methyl)-5-methyl-1H-benzo[d]imidazol-2-yl)-3,5-difluorobenzoic acid 
• 1308849-97-9 (R)-tert-butyl 2-((2-(2,6-difluoro-4-(methylcarbamoyl)phenyl)-5-methyl-lH-benzo[d]imidazol-l-yl)methyl)morpholine-4-carboxylate 
• 1400589-53-8 1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate 
• 1308849-86-6 (S)-methyl 2-((2-(2,6-difluoro-4-(methylcarbamoyl)phenyl)-5-methyl-1H-benzo[d]imidazol-1-yl)methyl)morpholine-4-carboxylate 
• 1308849-92-4 (S)-tert-butyl 2-((2-(2,6-difluoro-4-(methylcarbamoyl)phenyl)-5-methyl-1H-benzo[d]imidazol-1-yl)methyl)morpholine-4-carboxylate 

Relevant articles and documents

NOVEL PYRAZOLO-PYRROLO-PYRIMIDINE-DIONE DERIVATIVES AS P2X3 INHIBITORS

The present invention covers substituted Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

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