1175018-74-2 Usage
Description
N-2-propene-1-yl-3-chloro-cis-(R)-aminoindan, also known as N-Despropargyl N-(1-Chloroprop-1-ene) Rasagiline, is a derivative compound of Rasagiline mesylate (R126000). It is an irreversible monoamine oxidase B (MAO-B) inhibitor and exhibits antiparkinsonian properties.
Uses
Used in Pharmaceutical Industry:
N-2-propene-1-yl-3-chloro-cis-(R)-aminoindan is used as an intermediate in the preparation of Rasagiline mesylate and its chloro derivative impurities. It plays a crucial role in the synthesis of these compounds, which are used for the treatment of Parkinson's disease.
Used in Neurological Applications:
As an antiparkinsonian agent, N-2-propene-1-yl-3-chloro-cis-(R)-aminoindan is used for its neuroprotective and anti-inflammatory properties. It helps in managing the symptoms of Parkinson's disease by inhibiting the activity of MAO-B, an enzyme responsible for the breakdown of dopamine in the brain. This action leads to increased dopamine levels, thereby alleviating the motor symptoms associated with Parkinson's disease.
Check Digit Verification of cas no
The CAS Registry Mumber 1175018-74-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,5,0,1 and 8 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1175018-74:
(9*1)+(8*1)+(7*7)+(6*5)+(5*0)+(4*1)+(3*8)+(2*7)+(1*4)=142
142 % 10 = 2
So 1175018-74-2 is a valid CAS Registry Number.
1175018-74-2Relevant articles and documents
Rasagiline formulations and processes for their preparation
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Page/Page column 12-13, (2009/08/16)
The subject invention provides a pharmaceutical composition comprising N-propargyl-1(R)-aminoindan mesylate; a pharmaceutically acceptable carrier; and greater than 0.7 ppm but less than 30 ppm in total of a compound having the structure: and any salts of
