117556-62-4

Basic information

• Product Name: 2-Cyclohexen-1-ol, 1-methyl-4-(1-methylethyl)-, (1S,4S)-
• CAS NO: 117556-62-4
• Molecular Formula: C10H18O
• Molecular Weight: 154.252
• Mol File: 117556-62-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexen-1-ol, 1-methyl-4-(1-methylethyl)-, (1S,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexen-1-ol, 1-methyl-4-(1-methylethyl)-, (1S,4S)-(117556-62-4)
• EPA Substance Registry System: 2-Cyclohexen-1-ol, 1-methyl-4-(1-methylethyl)-, (1S,4S)-(117556-62-4)

Safety Data

• Hazardous Substances Data: 117556-62-4(Hazardous Substances Data)

Upstream product

• 5056-09-7 cis-piperitone epoxide 
• 1195-31-9 (+)-p-menth-1-ene 
• 203719-54-4 (1RS,2SR,4R)-limonene-1,2-epoxide 
• 851520-66-6 (+)-dihydrolimonene oxide 
• 5989-27-5 D-limonene 
• 851520-66-6 (3R)-3-isopropyl-6-methyl-7-oxabicyclo[4.1.0]heptane 
• 125627-55-6 (1S,2S,4R)-4-isopropyl-1-methyl-2-phenylselenenylcyclohexan-1-ol 
• 6909-13-3 trans N,N-dimethylamino-2 trans p-menthanol 
• 78478-85-0 (1S,2S,4R)-2-(dimethylamino)-1-methyl-4-(1-methylethenyl)cyclohexanol 
• 6909-30-4 (1S,2R,4R)-limonene-1,2-epoxide 
• 4942-88-5 (+)-1-Hydroxy-neo-dihydrocarveyl-acetat 
• 4680-31-3 1-Hydroxy-neocarvo-menthyl-acetat 
• 4680-25-5 (1R,3R,6S)-3-isopropyl-6-methyl-7-oxabicyclo[4.1.0]heptane 
• 2158-59-0 cryptone 

Downstream Products

• 877660-90-7 (-)-(1'S,2'S)-2'-isopropyl-5'-methyl-4-pentyl-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,6-diol 

Relevant articles and documents

PROCESS FOR THE SYNTHESIS OF CANNABIDIOL AND INTERMEDIATES THEREOF

The present invention relates to process for the preparation of cannabidiol (A) from the coupling of (D) and (E) through the intermediates (C) and (D) starting from compound (B). The invention further relates to the novel compounds (B), (C), (D) and (E) and reagents used in this process. More specifically, this invention provides the manufacturing of Cannabidiol (A) in milligram to gram or kilogram scale.

Synthesis of (1S,4R)-4-isopropyl-1-methyl-2-cyclohexen-1-ol, the aggregation pheromone of the ambrosia beetle Platypus quercivorus, its racemate, (1R,4R)- and (1S,4S)-isomers

(S)-Perillyl alcohol was converted to (R)-cryptone (91.5-93% ee) in six steps, which was then treated with methyllithium to give (1S,4R)-4-isopropyl-1-methyl-2-cyclohexen-1-ol, the aggregation pheromone of the ambrosia beetle Platypus quercivorus. The racemic pheromone was also prepared by methylation of (±)-cryptone. Both (1R,4R)- and (1S,4S)-isomers (98% ee) of the pheromone were synthesized from the enantiomers of dihydrolimonene oxide.