1177248-75-7Relevant articles and documents
Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines
Verhaeghe, Pierre,Azas, Nadine,Hutter, Sebastien,Castera-Ducros, Caroline,Laget, Michele,Dumetre, Aurelien,Gasquet, Monique,Reboul, Jean-Pierre,Rault, Sylvain,Rathelot, Pascal,Vanelle, Patrice
experimental part, p. 4313 - 4322 (2009/10/10)
To identify a new safe antiplasmodial molecular scaffold, an original series of 2-trichloromethylquinazolines, functionalized in position 4 by an alkyl- or arylamino substituent, was synthesized from 4-chloro-2-trichloromethylquinazoline 1, via a cheap, f