1177500-05-8Relevant articles and documents
Glycogen phosphorylase inhibitory effects of 2-oxo-1,2-dihydropyridin-3-yl amide derivatives
Karis, N. David,Loughlin, Wendy A.,Jenkins, Ian D.,Healy, Peter C.
experimental part, p. 4724 - 4733 (2009/12/01)
Glycogen phosphorylase (GP) plays a crucial role in the conversion of glycogen to glucose-1-phosphate (and in turn glucose) and is a promising target for therapeutic intervention in diabetes. In this study we synthesized new derivatives of 2-oxo-1,2-dihyd