117796-50-6

Basic information

• Product Name: Desloratadine IMpurity B
• Synonyms: Desloratadine IMpurity B;Desloratadine Related CoMpound A;Desloratadine USP Related Compound A;8-bromo-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
• CAS NO: 117796-50-6
• Molecular Formula: C19H19BrN2
• Molecular Weight: 355.27156
• Mol File: 117796-50-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 478.9±45.0 °C(Predicted)
• Appearance: /
• Density: 1.373±0.06 g/cm3(Predicted)
• PKA: 10.27±0.20(Predicted)
• CAS DataBase Reference: Desloratadine IMpurity B(CAS DataBase Reference)
• NIST Chemistry Reference: Desloratadine IMpurity B(117796-50-6)
• EPA Substance Registry System: Desloratadine IMpurity B(117796-50-6)

Safety Data

• Hazardous Substances Data: 117796-50-6(Hazardous Substances Data)

Usage

Description

Desloratadine IMpurity B, also known as 8-Deschloro-8-bromo Desloratadine, is an impurity of Loratadine (L469575). It is a chemical compound that may be used for the development of novel analytical applications.
Used in Pharmaceutical Industry:
Desloratadine IMpurity B is used as a reference material for the development of novel analytical applications for detecting impurities of Loratadine. This helps in ensuring the quality and purity of Loratadine, which is an antihistamine drug used for treating allergy symptoms.

Upstream product

• 932-77-4 3-bromobenzyl chloride 
• 130642-51-2 {3-[2-(3-Bromo-phenyl)-ethyl]-pyridin-2-yl}-(1-methyl-piperidin-4-yl)-methanone 
• 130642-57-8 8-Bromo-11-(1-methyl-piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine 
• 130642-47-6 3-[2-(3-Bromo-phenyl)-ethyl]-pyridine-2-carboxylic acid tert-butylamide 
• 130642-54-5 3-[2-(3-Bromo-phenyl)-ethyl]-pyridine-2-carbonitrile 
• 32998-95-1 N-tert-butyl-3-methylpyridine-2-carboxamide 
• 130642-60-3 4-(8-Bromo-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine-1-carboxylic acid ethyl ester 

Relevant articles and documents

Dual Antagonists of Platelet Activating Factor and Histamine. Identification of Structural Requirements for Dual Activity of N-Acyl-4-(5,6-dihydro-11H-benzocycloheptapyridin-11-ylidene)piperidines

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