117796-62-0

Basic information

• Product Name: (±)-11-(1-Acetyl-4-piperazinyl)-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine
• Synonyms: Sch-40338; (±)-1-Acetyl-4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperazine
• CAS NO: 117796-62-0
• Molecular Formula: C₂₀H₂₂ClN₃O
• Molecular Weight: 355.87084
• Mol File: 117796-62-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (±)-11-(1-Acetyl-4-piperazinyl)-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-11-(1-Acetyl-4-piperazinyl)-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine(117796-62-0)
• EPA Substance Registry System: (±)-11-(1-Acetyl-4-piperazinyl)-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine(117796-62-0)

Safety Data

• Hazardous Substances Data: 117796-62-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 13889-98-0 N-acetylpiperidine 
• 117810-66-9 8,11-Dichloro-6,11-Dihydro-5H-Benzo[5,6]Cyclo-Hepta[1,2-b]Pyridine 
• 133330-72-0 8-Chloro-6,11-Dihydro-11-Hydroxy-5H-Benzo[5,6]-Cyclohepta[1,2-b]Pyridine 
• 31251-41-9 8-chloro-5,6-dihydro-11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 

Relevant articles and documents

Dual antagonists of platelet activating factor and histamine. Part 3. Synthesis, biological activity and conformational implications of substituted N-acyl-bis-arylcycloheptapiperazines

A series of N-acyl-4-(5,6-dihydro-11-H-benzo[5,6]cyclohepta[1,2- b]pyridin-11-ylidene)piperazines is described that are dual antagonists of PAF and histamine. The structural requirements for activity in this series parallel those of their previously reported piperidinylidene counterparts. Whereas their global minimum energy conformations are different for both series of compounds, computer assisted molecular modeling suggests that a common bioactive conformation is possible.