117833-90-6

Basic information

• Product Name: (R)-2-amino-7-(Boc-amino)heptanoic acid
• CAS NO: 117833-90-6
• Molecular Weight: 260.334
• Mol File: 117833-90-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-2-amino-7-(Boc-amino)heptanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-amino-7-(Boc-amino)heptanoic acid(117833-90-6)
• EPA Substance Registry System: (R)-2-amino-7-(Boc-amino)heptanoic acid(117833-90-6)

Safety Data

• Hazardous Substances Data: 117833-90-6(Hazardous Substances Data)

Upstream product

• 133626-15-0 ((Z)-(R)-6-tert-Butoxycarbonylamino-1-hydroxymethyl-hex-2-enyl)-carbamic acid benzyl ester 
• 262278-05-7 tert-butyl (5-iodo-pentyl)-carbamate 
• 75178-90-4 N-(tert-butyloxycarbonyl)-5-aminopentanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 2508-29-4 5-hydroxypentylamine 
• 142342-55-0 diethyl {5-[(tert-butoxycarbonyl)amino]pentyl }-propanedioate 
• 929-17-9 7-aminoheptanoic acid 
• 60142-89-4 7-[(tert-butoxycarbonyl)amino]heptanoic acid 
• 117833-95-1 (R)-4-((Z)-5-tert-Butoxycarbonylamino-pent-1-enyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 117833-93-9 (Z)-(R)-N-Cbz-2,2-dimethyl-4-(4-cyano-1-butenyl)oxazolidine 
• 194718-13-3 [(S)-6-Azido-7-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-7-oxo-heptyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

ENANTIOSPECIFIC SYNTHESIS OF D-α,ω-DIAMINOALKANOIC ACIDS

An enantiospecific synthesis of D-Nω-Boc-α, ω-diaminoalkanoic acids starting from L-serine is described.

Synthesis method of double different protected amino acids

The invention relates to a synthesis method of double different protected amino acids.The technical problems of harsh reaction conditions, inapplicability of production enlarging and the like in an existing synthesis method are mainly solved. According to the technical scheme, the synthesis method of double different protected amino acids comprises the following steps: one of Boc20, Alloc-Cl or Cbz-Osuis added to amino alcohol under the action of an alkaline reagent to obtain a compound 1; the compound 1 reacts with methanesulfonyl chloride or paratoluensulfonyl chloride to obtain an intermediate, then a halide is added into acetone, heating and refluxing are executed to obtain a compound 2; the compound 2 is condensed with diethyl acetamidomalonate under the action of an alkaline agent togenerate a compound 3; the compound 3 is dissolved in alcohol and water, an inorganic base is added, heating, hydrolyzing and decarboxylating are executed to obtain a compound 4; acetylase is added into deionized water to obtain a compound 5 through enzymolysis; amino acid protection is executed, wherein one of Fmoc-Osu, Cbz-OSu, Alloc-Cl or Boc20 is added into thecompound 5 under the action of an alkaline agent to generatea target compound A.