117890-81-0

Basic information

• Product Name: 4-Chloro-7-methyl-pyrido[2,3-d]pyrimidine
• Synonyms: 4-Chloro-7-methyl-pyrido[2,3-d]pyrimidine
• CAS NO: 117890-81-0
• Molecular Formula: C₈H₆ClN₃
• Molecular Weight: 180
• Mol File: 117890-81-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• CAS DataBase Reference: 4-Chloro-7-methyl-pyrido[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-7-methyl-pyrido[2,3-d]pyrimidine(117890-81-0)
• EPA Substance Registry System: 4-Chloro-7-methyl-pyrido[2,3-d]pyrimidine(117890-81-0)

Safety Data

• Hazardous Substances Data: 117890-81-0(Hazardous Substances Data)

Usage

General Description

4-Chloro-7-methyl-pyrido[2,3-d]pyrimidine is a chemical compound with the molecular formula C8H6ClN3. It is a heterocyclic compound that is commonly used in the synthesis of pharmaceuticals and agrochemicals. 4-Chloro-7-methyl-pyrido[2,3-d]pyrimidine has a pyrido[2,3-d]pyrimidine core structure and contains a chloro and a methyl group as substituents. It is known for its potential as an antineoplastic agent, as well as its use in the synthesis of various compounds with biological activity. Additionally, it has been studied for its potential applications in the field of medicinal chemistry and drug discovery. Overall, 4-Chloro-7-methyl-pyrido[2,3-d]pyrimidine is an important chemical building block with potential applications in pharmaceutical and agrochemical industries.

Upstream product

• 30529-70-5 2-chloro-6-methyl nicotinic acid 
• 846021-26-9 2-amino-6-methyl nicotinic acid 
• 116598-87-9 7-methyl-pyrido[2,3-d]pyrimidin-4-ol 

Downstream Products

• 853680-63-4 (7R)-4-[7-methyl-8-(3,3,3-trifluoro-2-methoxy-2-phenyl-propionyl)-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidin-4-yl]-piperazine-1-carboxylic acid tert-butyl ester 
• 853680-62-3 (7S)-4-[7-methyl-8-(3,3,3-trifluoro-2-methoxy-2-phenyl-propionyl)-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidin-4-yl]-piperazine-1-carboxylic acid tert-butyl ester 
• 853680-66-7 (7S,2R)-{1-(4-chlorobenzyl)-2-[4-(7-methyl-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

AKT PROTEIN KINASE INHIBITORS

The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.