1181218-99-4

Basic information

• Product Name: (E)-2-(4-octen-4-yl)-5-phenyl-1,3,4-oxadiazole
• Synonyms: (E)-2-(4-octen-4-yl)-5-phenyl-1,3,4-oxadiazole
• CAS NO: 1181218-99-4
• Molecular Weight: 256.348
• Mol File: 1181218-99-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-octen-4-yl)-5-phenyl-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-octen-4-yl)-5-phenyl-1,3,4-oxadiazole(1181218-99-4)
• EPA Substance Registry System: (E)-2-(4-octen-4-yl)-5-phenyl-1,3,4-oxadiazole(1181218-99-4)

Safety Data

• Hazardous Substances Data: 1181218-99-4(Hazardous Substances Data)

Upstream product

• 825-56-9 2-phenyl-1,3,4-oxadiazole 
• 1942-45-6 4-Octyne 

Relevant articles and documents

Cobalt-catalyzed addition of azoles to alkynes

A ternary catalytic system consisting of a cobalt salt, a diphosphine ligand, and a Grignard reagent promotes syn-addition of an azole C(2)-H bond across an unactivated internal alkyne with high chemo-, regio-, and stereoselectivities under mild conditions. Mechanistic experiments suggest that the reaction involves oxidative addition of the oxazolyl C-H bond to the cobalt center, alkyne insertion into the Co-H bond, and reductive elimination of the resulting diorganocobalt species.