1181669-81-7

Basic information

• Product Name: 2-methyl-1-((4-nitrophenyl)sulfonyl)-1H-indole
• Synonyms: 2-methyl-1-((4-nitrophenyl)sulfonyl)-1H-indole
• CAS NO: 1181669-81-7
• Molecular Weight: 316.337
• Mol File: 1181669-81-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-methyl-1-((4-nitrophenyl)sulfonyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-1-((4-nitrophenyl)sulfonyl)-1H-indole(1181669-81-7)
• EPA Substance Registry System: 2-methyl-1-((4-nitrophenyl)sulfonyl)-1H-indole(1181669-81-7)

Safety Data

• Hazardous Substances Data: 1181669-81-7(Hazardous Substances Data)

Upstream product

• 6872-06-6 2-methyl indoline 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 

Downstream Products

• 1181669-86-2 2-[2-methyl-1-(4-nitrobenzenesulfonyl)-1H-indol-3-ylmethylene]malonic acid dimethyl ester 
• 1181669-87-3 2-[2-methyl-1-(4-nitrobenzenesulfonyl)-1H-indol-3-yl]cyclopropane-1,1-dicarboxylic acid dimethyl ester 
• 1181669-88-4 2-[2-bromomethyl-1-(4-nitrobenzenesulfonyl)-1H-indol-3-yl]cyclopropane-1,1-dicarboxylic acid dimethyl ester 
• 1181669-89-5 2-[2-formyl-1-(4-nitrobenzenesulfonyl)-1H-indol-3-yl]cyclopropane-1,1-dicarboxylic acid dimethyl ester 
• 1181669-84-0 2-methyl-1-(4-nitrobenzenesulfonyl)-1H-indole-3-carbaldehyde 

Relevant articles and documents

Selenium-catalyzed oxidative c(sp2)-h amination of alkenes exemplified in the expedient synthesis of (Aza-)indoles

A new selenium-catalyzed protocol for the direct, intramolecular amination of C(sp2)-H bonds using N-fluorobenzenesulfonimide as the terminal oxidant is reported. This method enables the facile formation of a broad range of diversely functionalized indoles and azaindoles derived from easily accessible ortho-vinyl anilines and vinylated aminopyridines, respectively. The procedure exploits the pronounced carbophilicity of selenium electrophiles for the catalytic activation of alkenes and leads to the formation of C(sp2)-N bonds in high yields and with excellent functional group tolerance.