118203-17-1

Basic information

• Product Name: 2-hydroxy-3-(hydroxymethyl)benzaldehyde
• Synonyms: 2-hydroxy-3-(hydroxymethyl)benzaldehyde
• CAS NO: 118203-17-1
• Molecular Weight: 152.15
• Mol File: 118203-17-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-3-(hydroxymethyl)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-3-(hydroxymethyl)benzaldehyde(118203-17-1)
• EPA Substance Registry System: 2-hydroxy-3-(hydroxymethyl)benzaldehyde(118203-17-1)

Safety Data

• Hazardous Substances Data: 118203-17-1(Hazardous Substances Data)

Upstream product

• 3328-69-6 2-hydroxy-isophthalaldehyde 
• 2937-59-9 2,6-bis(hydroxymethyl)phenol 

Downstream Products

• 1295646-18-2 2-(di(1H-indol-3-yl)methyl)-6-methoxyphenol 

Relevant articles and documents

Efficient Inhibition of Telomerase by Nickel–Salophen Complexes

Four nickel(II)–salophen complexes containing alkyl-imidazolium chains connected at the ortho or meta positions were prepared: N,N′-bis(2-hydroxy-4-methyl-3H-imidazol-1-iumbenzylideneamino)phenylenediamine (1), N,N′-bis(2-hydroxy-3-methyl-3H-imidazol-1-iumbenzylideneamino)phenylenediamine (2), N,N′-bis(2-hydroxy-3-methyl-3H-imidazol-1-iumbenzylideneamino)methyl-3H-imidazol-1-iumphenylenediamine (3), and N,N′-bis(2-hydroxy-4-methyl-3H-imidazol-1-iumbenzylideneamino)methyl-3H-imidazol-1-iumphenylenediamine (4). They protect G-quadruplex DNA (G4-DNA) against thermal denaturation and show KAvalues in the range of 7.4×105to 4×107m?1for G4-DNA models. Complex 4 exhibits an IC50value of 70 nm for telomerase inhibition.