1182846-71-4

Basic information

• Product Name: C₁₈H₁₇NO₃
• Synonyms: C₁₈H₁₇NO₃
• CAS NO: 1182846-71-4
• Molecular Weight: 295.338
• Mol File: 1182846-71-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₇NO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₇NO₃(1182846-71-4)
• EPA Substance Registry System: C₁₈H₁₇NO₃(1182846-71-4)

Safety Data

• Hazardous Substances Data: 1182846-71-4(Hazardous Substances Data)

Upstream product

• 612-61-3 7-chloroquinoline 
• 182163-96-8 3,4,5-trimethoxyphenylboronic Acid 

Relevant articles and documents

7-Chloroquinoline: a versatile intermediate for the synthesis of 7-substituted quinolines

A practical synthesis of 7-mono-substituted quinolines has been achieved. Selective reduction of the inexpensive commercial reagent 4,7-dichloroquinoline affords 7-chloroquinoline, which has been converted into more complex 7-mono-substituted quinolines through a series of Pd-catalyzed cross coupling reactions. These studies include the first examples of Suzuki reactions for the preparation of 7-mono-substituted quinolines as well as the first application of the Sonagashira reaction for the synthesis of 7-substituted quinolines. This strategy has been extended to the preparation of 2,7-di-substituted quinolines.