1183123-34-3

Basic information

• Product Name: 2-bromo-N-p-tolylbenzenesulfonamide
• Synonyms: 2-bromo-N-p-tolylbenzenesulfonamide
• CAS NO: 1183123-34-3
• Molecular Weight: 326.214
• Mol File: 1183123-34-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-bromo-N-p-tolylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N-p-tolylbenzenesulfonamide(1183123-34-3)
• EPA Substance Registry System: 2-bromo-N-p-tolylbenzenesulfonamide(1183123-34-3)

Safety Data

• Hazardous Substances Data: 1183123-34-3(Hazardous Substances Data)

Upstream product

• 2905-25-1 o-bromobenzenesulfonyl chloride 
• 106-49-0 p-toluidine 

Downstream Products

• 1186611-29-9 C₁₈H₂₁NO₂SSi 

Relevant articles and documents

Indole Synthesis through Sequential Electrophilic N-H and C-H Bond Activation Using Iodine(III) Reactivity

An intramolecular approach towards the regioselective construction of 2,3-diarylated indoles is reported. The reaction follows an intramolecular electrophilic N-H and C-H bond functionalization between the aniline and acetylene. This methodology employs the concept of a traceless tether to provide access to the free 2,3-diarylated indole products comprising a total of 18 examples. Hypervalent iodine reagents were identified as suitable promoters and four different protocols are provided, including stoichiometric and catalytic transformations.

Lewis acid catalyzed cascade reaction of 3-(2-benzenesulfonamide)propargylic alcohols to spiro[indene-benzosultam]s

A highly efficient and convenient construction of the spiro[indene-benzosultam] skeleton from propargylic alcohols has been developed. The reaction proceeded in a Lewis acid catalyzed cascade process, including the trapping of allene carbocation with sulfonamide, electrophilic cyclization, and intramolecular Friedel-Crafts alkylation. In the presence of NIS or NBS, iodo/bromo-substituted spiro[indene-benzosultam]s could be prepared in excellent yields.