118380-06-6 Usage
Description
METHYL N-SUCCINIMIDYL ADIPATE is a masked, amino reactive, heterobifunctional crosslinking reagent with a spacer arm of 7.2 Angstroms. It is a white solid and is used in various applications due to its chemical properties.
Uses
Used in Chemical Synthesis:
METHYL N-SUCCINIMIDYL ADIPATE is used as a crosslinking reagent for the formation of covalent bonds between molecules, allowing for the creation of stable and functional products.
Used in Pharmaceutical Industry:
METHYL N-SUCCINIMIDYL ADIPATE is used as a crosslinking agent for the development of drugs, particularly in the modification of proteins and peptides to enhance their stability, solubility, and bioavailability.
Used in Research and Development:
METHYL N-SUCCINIMIDYL ADIPATE is used as a research tool for studying the interactions between biomolecules, such as proteins and peptides, and their potential applications in drug discovery and development.
Used in Diagnostics:
METHYL N-SUCCINIMIDYL ADIPATE is used as a component in the development of diagnostic tools, such as immunoassays and biosensors, where its crosslinking properties can be utilized to improve the sensitivity and specificity of these devices.
Used in Material Science:
METHYL N-SUCCINIMIDYL ADIPATE is used as a crosslinking agent in the development of advanced materials, such as polymers and composites, with improved mechanical, thermal, and chemical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 118380-06-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,3,8 and 0 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 118380-06:
(8*1)+(7*1)+(6*8)+(5*3)+(4*8)+(3*0)+(2*0)+(1*6)=116
116 % 10 = 6
So 118380-06-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO6/c1-17-10(15)4-2-3-5-11(16)18-12-8(13)6-7-9(12)14/h2-7H2,1H3
118380-06-6Relevant articles and documents
P4 cap modified tetrapeptidyl α-ketoamides as potent HCV NS3 protease inhibitors
Sun, David X.,Liu, Lifei,Heinz, Beverly,Kolykhalov, Alexander,Lamar, Jason,Johnson, Robert B.,Wang, Q. May,Yip, Yvonne,Chen, Shu-Hui
, p. 4333 - 4338 (2007/10/03)
We describe herein the design, syntheses, and biological evaluation of new series of P4 tetrazole and adipic acid, ester, amide capped tetrapeptidyl α-ketoamide based HCV protease inhibitors.
Synthesis of Cluster Galactosides with High Affinity for the Hepatic Asialoglycoprotein Receptor
Biessen, Erik A.L.,Beuting, Diana M.,Roelen, Harlof C.P.F.,Marel, Gijs A. van de,Boom, Jacques H. van,Berkel, Theo J.C. van
, p. 1538 - 1546 (2007/10/02)
High-affinity ligands for the asialoglycoprotein receptor, which is uniquely localized on the parenchymal liver cell and recognizes oligoantennary galactosides, might be utilized as homing device to specifically target drugs or genes to paranchymal liver
Antibodies which catalyze hydrolysis of ester bonds
-
, (2008/06/13)
An analog-ligand having a conformation that substantially corresponds to the conformation of a hydrolytic transition state of an amide or ester reactant ligand is used to produce receptor molecules of predetermined specificity. The receptor molecules include an antibody combining site that binds to a reactant ligand and thereby stabilizes the tetrahedral carbon atom of the amide or ester hydrolysis transition state of that reactant ligand to catalytically hydrolyze the reactant ligand at a predetermined site.
