118460-48-3

Basic information

• Product Name: ethyl 2-fluoro-3-oxo-5-phenylpent-4-enoate
• Synonyms: ethyl 2-fluoro-3-oxo-5-phenylpent-4-enoate
• CAS NO: 118460-48-3
• Molecular Weight: 236.243
• Mol File: 118460-48-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-fluoro-3-oxo-5-phenylpent-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-fluoro-3-oxo-5-phenylpent-4-enoate(118460-48-3)
• EPA Substance Registry System: ethyl 2-fluoro-3-oxo-5-phenylpent-4-enoate(118460-48-3)

Safety Data

• Hazardous Substances Data: 118460-48-3(Hazardous Substances Data)

Upstream product

• 405-35-6 ethyl 2-fluoro-3-hydroxy-5-phenylpent-4-enoate 
• 104-55-2 3-phenyl-propenal 

Relevant articles and documents

Oxidation of Fluoroalkyl-Substituted Carbinols by the Dess-Martin Reagent

The efficient oxidation of mono-, di-, tri-, and perfluoroalkyl-substituted carbinols has been accommplished by the Dess-Martin periodinane oxidant.A variety of functional groups are compatible with the oxidation procedure.Monitoring the oxidation by 19F NMR indicated that a discreet periodinane intermediate is formed during the course of the reaction.Nonnucleophilic or sterically encumbered α-thiofluoro carbinols were readily oxidized; however, a nucleophilic α-thio-substituted trifluoromethyl carbinol was not.A tert-butyl alcohol modified periodinane oxidant was ultimately employed to achieve oxidation in this example.