1184850-54-1

Basic information

• Product Name: (1R)-2-[(6-chloropyrimidin-4-yl)amino]-1-phenylethanol
• Synonyms: (1R)-2-[(6-chloropyrimidin-4-yl)amino]-1-phenylethanol
• CAS NO: 1184850-54-1
• Molecular Weight: 249.7
• Mol File: 1184850-54-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R)-2-[(6-chloropyrimidin-4-yl)amino]-1-phenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R)-2-[(6-chloropyrimidin-4-yl)amino]-1-phenylethanol(1184850-54-1)
• EPA Substance Registry System: (1R)-2-[(6-chloropyrimidin-4-yl)amino]-1-phenylethanol(1184850-54-1)

Safety Data

• Hazardous Substances Data: 1184850-54-1(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 120443-82-5 (R)-2-phenyl-2-(trimethylsiloxy)acetonitrile 
• 1193-21-1 4,6-dichloropyrimidine 
• 2549-14-6 (R)-2-Amino-1-phenylethanol 

Downstream Products

• 1184846-99-8 (1R)-2-({6-[4-(ethyloxy)-3-(trifluoromethyl)phenyl]pyrimidin-4-yl}amino)-1-phenylethanol 

Relevant articles and documents

1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase

A series of 1-aryl-2-(((6-aryl)pyrimidin-4-yl)amino)ethanols have been found to be competitive inhibitors of fatty acid amide hydrolase (FAAH). One member of this class, JNJ-40413269, was found to have excellent pharmacokinetic properties, demonstrated robust central target engagement, and was efficacious in a rat model of neuropathic pain.