118495-07-1

Basic information

• Product Name: 7-(BENZYLOXY)-2-NAPHTHOL
• Synonyms: 7-(BENZYLOXY)-2-NAPHTHOL
• CAS NO: 118495-07-1
• Molecular Formula: C₁₇H₁₄O₂
• Molecular Weight: 250.29
• Mol File: 118495-07-1.mol
• Article Data: 13

Chemical Properties

• Melting Point: 151-152°C
• Boiling Point: 444.1°Cat760mmHg
• Flash Point: 279.2°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 1.68E-08mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: 7-(BENZYLOXY)-2-NAPHTHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(BENZYLOXY)-2-NAPHTHOL(118495-07-1)
• EPA Substance Registry System: 7-(BENZYLOXY)-2-NAPHTHOL(118495-07-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 118495-07-1(Hazardous Substances Data)

Usage

General Description

"7-(Benzyloxy)-2-naphthol" is a chemical compound that generally belongs to the class of organic compounds known as 1-benzyl-2-naphthols. These are aromatic compounds containing a 2-naphthol substituted at the C1 position by a benzyl group. Its systematic name is "7-(Benzyloxy)naphthalen-2-ol". As a scientific reagent, it is often used in a variety of complex organic syntheses. Specific information about its other intrinsic properties such as boiling point, melting point, density, solubility, and chemical structure largely depends on the conditions under which it is stored and used.

InChI:InChI=1/C17H14O2/c18-16-8-6-14-7-9-17(11-15(14)10-16)19-12-13-4-2-1-3-5-13/h1-11,18H,12H2

Upstream product

• 582-17-2 2,7-Dihydroxynaphthalene 
• 100-44-7 benzyl chloride 
• 146744-23-2 2-acetoxy-7-hydroxynaphthalene 
• 1257230-84-4 2-acetoxy-7-benzyloxynaphthalene 
• 100-39-0 benzyl bromide 

Downstream Products

• 118494-97-6 (R)-7,7-bis(benzyloxy)-2,2'-dihydroxy-1,1'-binaphthyl 
• 118494-97-6 (S)‐7,7′‐bis(benzyloxy)‐[1,1′‐binaphthalene]‐2,2′‐diol 
• 118494-97-6 ()-7,7'-bis-benzyloxy-[1,1']-binaphthalene-2,2'-diol 
• 317806-79-4 ethyl 2-(((7-benzyloxy)naphthalene)oxy)acetate 
• 106752-98-1 7-(benzyloxy)-2-hydroxy-1-naphthaldehyde 
• 566872-44-4 2-hydroxy-7-benzyloxy-1-nitronaphthalene 
• 170889-47-1 diphenyl 2,2'-dihydroxy-[1,1'-binaphthalene]-3,3'-dicarboxylate 
• 866603-15-8 (+)-7-(benzyloxy)-2-naphthyl (R)-2-[4-(benzyloxy)phenyloxy]propionate 
• 613-62-7 2-benzyloxynaphthalene 
• 866603-16-9 (+)-7-hydroxy-2-naphthyl (R)-2-(4-hydroxyphenyloxy)propionate 
• 866603-18-1 (+)-7-(3-fluoro-4-hydroxybenzoyloxy)-2-naphthyl (R)-2-[4-(3-fluoro-4-hydroxybenzoyloxy)phenyloxy]propionate 
• 866603-17-0 (+)-7-(3-fluoro-4-benzyloxybenzoyloxy)-2-naphthyl (R)-2-[4-(3-fluoro-4-benzyloxybenzoyloxy)phenyloxy]propionate 
• 317806-81-8 methyl 3α,12α-bis(2-((7-benzyloxy)naphthyloxy)acetyloxy)-5β-cholan-24-oate 
• 317806-80-7 2-((7-benzyloxy)naphthyloxy)acetic acid 

Relevant articles and documents

Enantioselective iron/bisquinolyldiamine ligand‐catalyzed oxidative coupling reaction of 2‐naphthols

An iron‐catalyzed asymmetric oxidative homo‐coupling of 2‐naphthols for the synthesis of 1,1′‐Bi‐2‐naphthol (BINOL) derivatives is reported. The coupling reaction provides enantioenriched BINOLs in good yields (up to 99%) and moderate enantioselectivities (up to 81:19 er) using an iron‐complex generated in situ from Fe(ClO4)2 and a bisquinolyldiamine ligand [(1R,2R)‐N1,N2‐di(quinolin‐8‐yl)cyclohexane‐1,2‐diamine, L1]. A number of ligands (L2–L8) and the analogs of L1, with various substituents and chiral backbones, were synthesized and examined in the oxidative coupling reactions.

Lewis Acid-Mediated Cyanation of Phenols Using N-Cyano-N-phenyl-p-toluenesulfonamide

Lewis acid-mediated cyanation of phenol derivatives with N-cyano-N-phenyl-p-toluenesulfonamide (NCTS) has been developed. The reaction proceeded efficiently with high regioselectivity to produce aromatic nitriles in moderate to excellent yields, which provides a direct and practical access to valuable products. (Figure presented.).

Regioselective O-alkylations and acylations of polyphenolic substrates using a calix[4]pyrrole derivative

The 10α,20α-bis(4-nitrophenyl)-calix[4]pyrrole 2 can act as a topologically selective protecting group in the O-alkylation and acylation of polyphenolic polycyclic aromatic compounds thanks to the regioselective formation of phenolate-type complexes. Rema