118555-84-3 Usage
General Description
Floribundone 1 is a chemical compound that falls under the class of diterpenoids. It is isolated from the flowers of the plant Taxodium floridanum. Floribundone 1 has been identified as a potent inhibitor of the enzyme protein farnesyltransferase, which plays a key role in the post-translational modification of proteins. Floribundone 1 has demonstrated promising anti-cancer activities, particularly in leukemia cells, by disrupting the farnesylation process of certain proteins that are crucial for cancer cell proliferation and survival. The discovery of Floribundone 1 and its inhibitory activity against protein farnesyltransferase holds potential for the development of novel anti-cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 118555-84-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,5,5 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 118555-84:
(8*1)+(7*1)+(6*8)+(5*5)+(4*5)+(3*5)+(2*8)+(1*4)=143
143 % 10 = 3
So 118555-84-3 is a valid CAS Registry Number.
118555-84-3Relevant articles and documents
Bitetrahydroanthracenes from flowers of Cassia torosa Cav.
Kitanaka,Takido
, p. 2588 - 2590 (2007/10/02)
A new bitetrahydroanthracene derivative, torosaol-III, was isolated from the flowers of Cassia torosa Cav. along with physcion, 5,7'-physcionanthrone-physcion, 5,7'-biphyscion, torosanin-9,10-quinone, 5,7-dihydroxychromone, naringenin, and chrysoeriol. The structure of torosaol-III was established as 3,3',4,4'-tetrahydro-3,3',8,8',9,9'-hexahydroxy-6,6'-dimethoxy-3,3'-di methyl-1(2H),1'(2H)-5,7'-bianthracenone on the basis of spectral and chemical evidence. Dimeric tetrahydroanthracenes exhibited cytotoxic activity against KB cells in the tissue culture.