118578-84-0 Usage
General Description
Phosphonic acid, [[4-(acetylamino)phenyl]methyl]-, diethyl ester is a chemical compound with potential applications in organic synthesis and pharmaceutical research. It is the diethyl ester form of 4-(acetylamino)phenylmethyl phosphonic acid, which is a phosphonic acid derivative. This chemical is commonly used as a building block in the synthesis of various organic molecules and can also be used as a pharmaceutical intermediate. Its structure and properties make it useful in the design and development of new drugs and biologically active compounds. Additionally, it can be used to modify the surface properties of materials in various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 118578-84-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,5,7 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 118578-84:
(8*1)+(7*1)+(6*8)+(5*5)+(4*7)+(3*8)+(2*8)+(1*4)=160
160 % 10 = 0
So 118578-84-0 is a valid CAS Registry Number.
118578-84-0Relevant articles and documents
Negative inotropic activity of para-substituted diethyl benzylphosphonates related to fostedil
Bellucci, Christina,Gualtieri, Fulvio,Chiarini, Alberto
, p. 473 - 478 (1987)
Several para-substituted diethyl benzylphosphonates related to the calcium antagonist diethyl 4-(2-benzothiazolyl)benzylphosphonate (fostedil) have been studied.They produce a dose-dependent negative inotropic effect on left atrial muscle isolated from guinea pig heart.Some of the compounds are equipotent or slightly more potent than fostedil and diltiazem taken as reference drugs.Structure-activity relationships are discussed.Keywords: calcium antagonists / p-substituted diethyl benzylphosphonates / cardiodepressant activity