1186139-57-0

Basic information

• Product Name: C₁₉H₂₉ClN₃OP
• Synonyms: C₁₉H₂₉ClN₃OP
• CAS NO: 1186139-57-0
• Molecular Weight: 381.886
• Mol File: 1186139-57-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₉ClN₃OP(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₉ClN₃OP(1186139-57-0)
• EPA Substance Registry System: C₁₉H₂₉ClN₃OP(1186139-57-0)

Safety Data

• Hazardous Substances Data: 1186139-57-0(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1434076-71-7 C₂₂H₃₃ClN₃O₃P 
• 1310539-62-8 C₂₀H₃₀ClN₄OP 
• 1281868-06-1 C₂₄H₃₉ClN₃OPS₂ 
• 1281868-05-0 C₂₃H₃₇ClN₃OPS₂ 
• 1186139-69-4 C₃₆H₄₆ClN₄O₃P 

Relevant articles and documents

Group-Assisted Purification Chemistry for Asymmetric Mannich-type Reaction of Chiral N-Phosphonyl Imines with Azlactones Leading to Syntheses of α-Quaternary α,β-Diamino Acid Derivatives ?

An asymmetric Mannich-type reaction between chiral N-phosphonyl imines and azlactones [oxazol-5(4H)-ones] has been established under convenient conditions at room temperature. The reaction was performed without using any bases, additives, or catalysts to achieve up to excellent chemical yields and diastereoselectivity for 32 examples. The α-quaternary syn-α,β-diamino acid products were purified simply by washing the crude mixtures with cosolvents, following the group-assisted purification chemistry/technology, without involving traditional chromatography or recrystallization methods. The auxiliary can be readily removed and recycled for reuse. The absolute configuration was unambiguously assigned by X-ray structural analysis.