1186414-49-2Relevant articles and documents
Characterization of FK506 biosynthetic intermediates involved in post-PKS elaboration
Ban, Yeon Hee,Shinde, Pramod B.,Hwang, Jae-Yeon,Song, Myoung-Chong,Kim, Dong Hwan,Lim, Si-Kyu,Sohng, Jae Kyung,Yoon, Yeo Joon
, p. 1091 - 1098 (2013)
The post-PKS modification steps of FK506 biosynthesis include C9-oxidation and 31-O-methylation, but the sequence of these reactions and the exact route have remained unclear. This study details the post-PKS modification pathways in FK506 biosynthesis thr