1187-04-8Relevant articles and documents
Synthesis of a stereoisomeric mixture of 2,3-dihydro-2,3,5-trimethyl-6-(1-methyl-2-oxobutyl)-4H-pyran-4-one, the pheromone of the drugstore beetle
Sakakibara,Mori
, p. 2401 - 2402 (1979)
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USE OF BIOLOGICAL SYSTEMS FOR THE PREPARATION OF CHIRAL MOLECULES IV : A TWO-STEP CHEMOENZYMATIC SYNTHESIS OF A NATURAL PHEROMONE (4R,5S)-(-)-4-METHYL 5-HYDROXY HEPTAN 3-ONE, SITOPHILURE.
Fauve, Annie,Veschambre, Henri
, p. 5037 - 5040 (1987)
Reduction of 4-methyl heptan 3,5-dione 2 by resting cells of Geotrichum candidum provides natural sitophilure (4R,5S)-(-)-4-methyl 5-hydroxy heptan 3-one 1 under anaerobic conditions.Diastereoisomer (4S,5S)-(+)-4-methyl 5-hydroxy heptan 3-one 1a is obtained under aerobic conditions.Starting β-diketone is easily obtained by a one-pot synthesis.Good yield and high enantiomeric excess are obtained for the natural pheromone.
Synthesis of all four stereoisomers of 5-hydroxy-4-methyl-3-heptanone using plants and oyster mushrooms
Bohman, Bj?rn,Unelius, C. Rikard
, p. 8697 - 8701 (2009)
All four possible stereoisomers of 5-hydroxy-4-methyl-3-heptanone were synthesized from common achiral reagents using fast, straightforward organic synthesis, including the use of whole tissue of Daucus carota, Solanum melongena, and Pleurotus ostreatus.
Method for preparing 2-methyl-1,3-dicarbonyl derivative
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Paragraph 0043, (2016/10/08)
The invention discloses a method for preparing a 2-methyl-1,3-dicarbonyl derivative. A 1,3-dicarbonyl derivative serves as an initiator, raw materials are easy to obtain, and a great variety of raw materials are available. The product obtained through the method has high type diversity and can be used directly or used for other further reactions. Besides, only organic peroxides and a catalytic amount of inorganic copper salt are used, so that cost is low. According to the method, a reaction is conducted in air, reaction conditions are mild, pollution is small, reaction time is short, the yield of the target product is high, reaction operation and aftertreatment are easy, and the method is suitable for industrial production.