1187-81-1

Basic information

• Product Name: 5-chloro-3-methyl-pentan-2-one
• Synonyms: 2-pentanone, 5-chloro-3-methyl-; 5-Chloro-3-methylpentan-2-one
• CAS NO: 1187-81-1
• Molecular Formula: C₆H₁₁ClO
• Molecular Weight: 134.6039
• Mol File: 1187-81-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 180.7°C at 760 mmHg
• Flash Point: 80.2°C
• Density: 0.986g/cm³
• Vapor Pressure: 0.886mmHg at 25°C
• Refractive Index: 1.422
• CAS DataBase Reference: 5-chloro-3-methyl-pentan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-3-methyl-pentan-2-one(1187-81-1)
• EPA Substance Registry System: 5-chloro-3-methyl-pentan-2-one(1187-81-1)

Safety Data

• Hazardous Substances Data: 1187-81-1(Hazardous Substances Data)

Upstream product

• 1123-19-9 3-acetyl-3-methyl-dihydro-furan-2-one 
• 1124-92-1 5-chloro-3-methylpentan-2-one ethylene acetal 
• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 

Downstream Products

• 1567-75-5 1-(1-methylcyclopropyl)ethanone 
• 78584-51-7 2-(3-methyl-4-oxopentyl)isoindoline-1,3-dione 
• 78584-42-6 5-benzylmethylamino-3-methyl-2-pentanone 
• 78584-62-0 cis-3-acetyl-1,3-dimethyl-3-(3,4,5-trimethoxyphenyl)pyrrolidine 
• 78187-35-6 cis-3-isopropenyl-1,3-dimethyl-2-(3,4,5-trimethoxyphenyl)pyrrolidine 
• 78584-64-2 cis-3-(2-hydroxy-2-propyl)-1,3-dimethyl-2-(3,4,5-trimethoxyphenyl)pyrrolidine 
• 78584-59-5 cis-3-acetyl-3-methyl-2-(3,4,5-trimethoxyphenyl)pyrrolidine 
• 78584-56-2 4,4-ethylenedioxy-3-methyl-N-(3,4,5-trimethoxybenzylidene)pentylamine 
• 78584-60-8 cis-2-(p-chlorophenyl)-3-(1,1-ethylenedioxyethyl)-1,3-dimethylpyrrolidine 
• 78584-66-4 cis-2-(p-chlorophenyl)-3-(1,1-ethylenedioxyethyl)-3-methylpyrrolidine 
• 78584-61-9 cis-3-acetyl-2-(p-chlorophenyl)-1,3-dimethylpyrrolidine 
• 78187-36-7 cis-2-(p-chlorophenyl)-3-isopropenyl-1,3-dimethylpyrrolidine 
• 78584-63-1 cis-(p-chlorophenyl)-3-(2-hydroxy-2-propyl)-1,3-dimethylpyrrolidine 
• 78597-57-6 4,4-ethylenedioxy-3-methyl-N-(p-chlorobenzylidene)pentylamine 

Relevant articles and documents

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Pentazocine prodrug as well as preparation method and application thereof

The invention discloses a pentazocine prodrug shown as a formula (I), a preparation method thereof and medical application of a pharmaceutical preparation containing the pentazocine prodrug, wherein Ris hydrogen or deuterium. The water solubility of the prodrug compound is improved by 20 times or above at room temperature, the prodrug compound is chemically stable, the onset time is delayed, thedrug effect is prolonged, meanwhile, the same parent drug blood concentration is generated at a low dosage, and the prodrug compound has a wide clinical application prospect.

Mechanistic organic chemistry in a microreactor. Zeolite-controlled photooxidations of organic sulfides

The intrazeolite and solution photooxygenations of a series of sulfides have been compared. The unusual zeolite environment enhances the rates of reaction, it suppresses the Pummerer rearrangements, and it has a dramatic effect on the sulfoxide/sulfone ratio. A detailed kinetic study utilizing trapping experiments and intramolecular competition provides evidence for cation complexation to a persulfoxide intermediate as the underlying phenomenon for the unique intrazeolite behavior. For example, the enhanced rate of reaction is traced to the cation stabilization of the persulfoxide toward unproductive decomposition to substrate and triplet oxygen.

Use of xanthine derivatives for the treatment of nerve damage following an interruption in blood circulation

Use of xanthine derivatives for the treatment of nerve damage following an interruption in blood circulation. The invention relates to the use of xanthine derivatives of the formula I STR1 in which R2 is a (C1 -C4)-alkyl group and at least one of the symbols R1 and R3 is a radical of the formula II or III STR2 in which A is CHOH, CO or dioxolane, R4 is a hydrogen atom or a (C1 -C4)-alkyl group and n is 0 to 5, and in which R5 and R6 are hydrogen atoms or (C1 -C4)-alkyl groups or, together with the nitrogen atom to which they are bonded, form a 5- to 7-membered ring, it being possible for one carbon atom to be replaced by an oxygen or nitrogen atom, m is 1 or 2 and the other radical R1 or R3, if appropriate, is a hydrogen atom, a (C1 -C6)-alkyl group or a (C3 -C6)-alkenyl group, for the preparation of medicaments for the prophylaxis and treatment of nerve damage following an interruption in blood circulation, and novel xanthine derivatives, and to processes for their preparation.