118757-37-2

Basic information

• Product Name: 5-(4-Methoxy-phenyl)-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine
• Synonyms: 5-(4-Methoxy-phenyl)-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine
• CAS NO: 118757-37-2
• Molecular Weight: 304.351
• Mol File: 118757-37-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(4-Methoxy-phenyl)-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-Methoxy-phenyl)-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine(118757-37-2)
• EPA Substance Registry System: 5-(4-Methoxy-phenyl)-7-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine(118757-37-2)

Safety Data

• Hazardous Substances Data: 118757-37-2(Hazardous Substances Data)

Upstream product

• 61-82-5 3⁽⁵⁾-amino-1,2,4-triazole 
• 959-23-9 4'-methoxychalcone 
• 61-82-5 3-amino-1,2,4-triazole 

Downstream Products

• 118787-62-5 7-phenyl-5-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine 

Relevant articles and documents

Imine-Enamine Tautomerism Of Dihydroazolopyrimidines 5. Steric Effects And The Tautomeric Equilibrium For Dihydro-1,2,4-Triazolopyrimidines

The reaction of 3-amino-1,2,4-triazole with β-dimethylaminopropiophenones or unsaturated ketones gives 5,7-disubstituted 4,7(6,7)-dihydro-1,2,4-triazolopyrimidines.An increase in the bulk of the substituent at C(7) in the bicyclic system leads to relative stabilization of the enamine tautomer of these compounds.An x-ray diffraction structural analysis of 7-tert-butyl-5-(4-methoxyphenyl)-4,7-dihydro-1,2,4-triazolopyrimidine showed that the introduction of a tert-butyl group into the dihydropyrimidine ring leads to significant loss of planarity of this system.