1187627-61-7Relevant articles and documents
Pd-catalyzed domino reactions of nitroaromatics: A surrogate access towards the saturated N-heterocycles
Vodnala, Nagaraju,Kaldhi, Dhananjaya,Polina, Saibabu,Putta, V.P. Rama Kishore,Gupta, Richa,Promily, S.C. Pinky,Linthoinganbi,Singh, Virender,Malakar, Chandi C.
, p. 5695 - 5699 (2016)
Using Pd/HCOOCs as a surrogate reagents synthesis of saturated N-heterocycles was described from nitroaromatics as starting materials. The developed new reaction conditions exclude the generally used toxic reagents like carbon monoxide as deoxygenative agent. The developed protocol permits the synthesis privileged bioactive N-heterocyclic scaffolds in good yields and selectivity.
An odorless, one-pot synthesis of nitroaryl thioethers via SNAr reactions through the in situ generation of S-alkylisothiouronium salts
Lu, Guo-Ping,Cai, Chun
, p. 59990 - 59996 (2015/02/19)
A newly developed C-S bond formation nucleophilic aromatic substitution (SNAr) reaction in aqueous Triton X-100 (TX100) micelles has been disclosed. This chemistry, in which odorless, cheap and stable thiourea in place of thiols is used as the sulfur reagent, provides an efficient approach for the generation of nitroaryl thioethers, which are useful structural units of many bioactive molecules, rendering this methodology attractive to both synthetic and medicinal chemistry.
