1188-58-5 Usage
Description
1,2-Distearoyl-rac-glycerol, also known as Glyceryl 1,2-Distearate, is a lipid compound derived from glycerol and stearic acid. It is characterized by its lipophilic nature and is commonly used in pharmaceutical formulations.
Uses
Used in Pharmaceutical Industry:
1,2-Distearoyl-rac-glycerol is used as a component in the preparation of liposomes for drug delivery, specifically for topically delivered drugs. Its lipophilic properties allow for the encapsulation and controlled release of active ingredients, enhancing their efficacy and stability.
Additionally, 1,2-Distearoyl-rac-glycerol is used as a component in the preparation of lipophilic peptides for gene delivery. This application leverages its ability to facilitate the transport of genetic material into target cells, potentially improving the effectiveness of gene therapy treatments.
Purification Methods
Crystallise the glyceride from chloroform/pet ether. [cf p 678, Beilstein 2 IV 1231.]
Check Digit Verification of cas no
The CAS Registry Mumber 1188-58-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1188-58:
(6*1)+(5*1)+(4*8)+(3*8)+(2*5)+(1*8)=85
85 % 10 = 5
So 1188-58-5 is a valid CAS Registry Number.
InChI:InChI=1/C38H74O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-36(40)42-38(35-39)43-37(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h38-39H,3-35H2,1-2H3