118805-87-1Relevant articles and documents
Iodoferrocene as a partner inN-arylation of amides
Kadari, Lingaswamy,Erb, William,Roisnel, Thierry,Radha Krishna, Palakodety,Mongin, Florence
, p. 15928 - 15941 (2020/10/08)
In this study, we developed a convenient methodology for theN-arylation of various acetamides, benzamides and related compounds by iodoferrocene. Optimization of the reaction was first performed from acetamide on the basis of the achievements in the benzene series. Next, the identified conditions (use of copper(i) iodide,N,N′-dimethylethylenediamine, tripotassium phosphate in dioxane at 90 °C for 14 h) were applied to different aliphatic/aromatic primary and cyclic/acyclic secondary amides in order to determine the scope of the reaction, thus easily generating a small library of ferrocene amides.