1188337-62-3

Basic information

• Product Name: 2-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-acrylic acid ethyl ester
• Synonyms: 2-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-acrylic acid ethyl ester
• CAS NO: 1188337-62-3
• Molecular Weight: 350.347
• Mol File: 1188337-62-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-acrylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-acrylic acid ethyl ester(1188337-62-3)
• EPA Substance Registry System: 2-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}-acrylic acid ethyl ester(1188337-62-3)

Safety Data

• Hazardous Substances Data: 1188337-62-3(Hazardous Substances Data)

Upstream product

• 504437-66-5 (S)‐N‐((3‐(3‐fluoro‐4‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)phenyl)‐2‐oxooxazolidin‐5‐yl)methyl)acetamide 
• 5459-35-8 2-bromo-acrylic acid ethyl ester 

Downstream Products

• 1188337-63-4 2-{4-[(S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenyl}3-(2-bromo-4-nitro-imidazol-1-yl)-propionic acid ethyl ester 
• 1188337-64-5 N-(S)-(3-{4-[2-(2-bromo-4-nitro-imidazol-1-yl)-1-hydroxymethyl-ethyl]-3-fluoro-phenyl}-2-oxo-oxazolidin-5-ylmethyl)acetamide 
• 1188918-66-2 N-(S)-{3-[3-fluoro-4-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}acetamide 

Relevant articles and documents

BICYCLIC NITROIMIDAZOLES COVALENTLY LINKED TO SUBSTITUTED PHENYL OXAZOLIDINONES

The current invention provides a series of bicyclic nitroimidazole- substituted phenyl oxazolidinones in which a bicyclic nitroimidazole pharmacophore is covalently bonded to a phenyl oxazolidinone, their pharmaceutical compositions, and the method of use of the compositions for prevention and treatment of bacterial infections. The bicyclic nitroimidazole-substituted phenyl oxazolidinones possess surprising antibacterial activity against wild- type and resistant strains of pathogens, and are therefore useful for the prevention, control and treatment of a number of human and veterinary bacterial infections caused by these pathogens, such as Mycobacterium tuberculosis.