1188413-97-9

Basic information

• Product Name: (Z)-4-methoxymethyl-5-(2-methylbenzylidene)furan-2(5H)-one
• Synonyms: (Z)-4-methoxymethyl-5-(2-methylbenzylidene)furan-2(5H)-one
• CAS NO: 1188413-97-9
• Molecular Weight: 230.263
• Mol File: 1188413-97-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-4-methoxymethyl-5-(2-methylbenzylidene)furan-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-methoxymethyl-5-(2-methylbenzylidene)furan-2(5H)-one(1188413-97-9)
• EPA Substance Registry System: (Z)-4-methoxymethyl-5-(2-methylbenzylidene)furan-2(5H)-one(1188413-97-9)

Safety Data

• Hazardous Substances Data: 1188413-97-9(Hazardous Substances Data)

Upstream product

• 766-47-2 1-ethynyl-2-methylbenzene 
• 244141-48-8 (Z)-3-iodo-4-methoxybut-2-enoic acid 

Relevant articles and documents

Copper-catalyzed preparation of γ-alkylidenebutenolides and isocoumarins under mild palladium-free conditions

A general and efficient copper(I)-catalyzed cross-coupling and heterocyclization reaction of terminal alkynes and β-iodo-α,β- unsaturated acid derivatives has been developed under very mild conditions. This method provides easy access from good to excellent yields of a variety of 5-ylidenebutenolides and 3-substituted isocoumarins with excellent regio- and stereoselectivity. This procedure does not require the use of any expensive supplementary additives, and is palladium-free.