1188513-95-2

Basic information

• Product Name: 1-(4-(2H-indazol-2-yl)phenyl)ethan-1-one
• Synonyms: 1-(4-(2H-indazol-2-yl)phenyl)ethan-1-one
• CAS NO: 1188513-95-2
• Molecular Weight: 236.273
• Mol File: 1188513-95-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(4-(2H-indazol-2-yl)phenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(2H-indazol-2-yl)phenyl)ethan-1-one(1188513-95-2)
• EPA Substance Registry System: 1-(4-(2H-indazol-2-yl)phenyl)ethan-1-one(1188513-95-2)

Safety Data

• Hazardous Substances Data: 1188513-95-2(Hazardous Substances Data)

Upstream product

• 552-89-6 2-nitro-benzaldehyde 
• 99-92-3 p-aminobenzophenone 
• 92437-70-2 C₁₅H₁₂N₂O₃ 
• 271-42-1 2H-indazole 
• 149104-90-5 4-acetylphenylboronic acid 
• 612-24-8 o-nitrobenzonitrile 

Relevant articles and documents

Manganese-Catalyzed Electrochemical Tandem Azidation-Coarctate Reaction: Easy Access to 2-Azo-benzonitriles

A one-pot cascade transformation consisting of an electrochemically driven azidation of 2H-indazole followed by coarctate fragmentation is developed to synthesize the 2-azo-benzonitrile motif. This manganese-catalyzed transformation is external-chemical-oxidant-free and operates at ambient temperature under air. This methodology exhibits good functional group tolerance, affording a broad range of substrate scopes of up to 89% isolated yield. Diverse derivatization of the 2-azo-benzonitrile product resulted in other valuable scaffolds.

BTK INHIBITOR

Provided are a series of BTK inhibitors, and specifically disclosed are a compound, pharmaceutically acceptable salt thereof, tautomer thereof or prodrug thereof represented by formula (I), (II), (III) or (IV).