118863-83-5

Basic information

• Product Name: 3-phenyl-5-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole
• Synonyms: 3-phenyl-5-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole
• CAS NO: 118863-83-5
• Molecular Weight: 289.26
• Mol File: 118863-83-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-phenyl-5-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-5-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole(118863-83-5)
• EPA Substance Registry System: 3-phenyl-5-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole(118863-83-5)

Safety Data

• Hazardous Substances Data: 118863-83-5(Hazardous Substances Data)

Upstream product

• 2740-83-2 3-(TRIFLUOROMETHYL)BENZYLAMINE 
• 3357-37-7 benzaldehyde diaminomethylenehydrazone 
• 98-08-8 α,α,α-trifluorotoluene 
• 80670-36-6 3-diazo-5-phenyl-3H-1,2,4-triazole 

Relevant articles and documents

Iodine Catalyzed Oxidative Coupling of Diaminoazines and Amines for the Synthesis of 3,5-Disubstituted-1,2,4-Triazoles

A simple, convenient, transition metal-free one pot synthesis of 3,5-disubstituted-1,2,4-triazoles has been established. The innovation in this reaction is the use of easily available 1,1-diaminoazines as substrates. This method provides the products with wider substrate scope, at an expedited rate, and with relatively better yields in comparison to the reported methods. The reaction mechanism involves an initial intermolecular nucleophilic addition (facilitated by I2) followed by intramolecular nucleophilic cyclization.