118908-11-5

Basic information

• Product Name: ether silyle du coriolate de methyle
• CAS NO: 118908-11-5
• Molecular Weight: 548.882
• Mol File: 118908-11-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ether silyle du coriolate de methyle(CAS DataBase Reference)
• NIST Chemistry Reference: ether silyle du coriolate de methyle(118908-11-5)
• EPA Substance Registry System: ether silyle du coriolate de methyle(118908-11-5)

Safety Data

• Hazardous Substances Data: 118908-11-5(Hazardous Substances Data)

Upstream product

• 128860-92-4 tert-Butyl-[(R)-1-((E)-3,3-dimethoxy-propenyl)-hexyloxy]-diphenyl-silane 
• 119009-01-7 (E)-(R)-1,1-Dimethoxy-non-2-en-4-ol 
• 109296-10-8 4-hydroxy-trans-2-nonenal-dimethylacetal 
• 67878-16-4 (8-methoxycarbonyloctyl)triphenylphosphonium bromide 
• 118908-15-9 (E)-(S)-4-(tert-Butyl-diphenyl-silanyloxy)-non-2-enal 
• 693-25-4 n-pentylmagnesium bromide 

Downstream Products

• 10219-70-2 (13R)-hydroxylinoleic acid methyl ester 

Relevant articles and documents

Syntheses stereoselectives de metabolites hydroxyles d'acides gras polyinsatures

The E,Z dienol structure is characteristic of the basic structure of most of the polyunsaturated fatty acid metabolites.In this paper are described our results concerning a new approach towards molecules of this type.The key features of this strategy include: 1) the use of the, easily available, fumaraldehyde monodimethylacetal 4 as a key intermediate for the synthesis of such compounds in racemic form and 2) the use of the chiral sorbic acid tricarbonyl ion complex 8 as a resolving agent.The methodology allows then the synthesis of several fatty acid metabolites such as 4-hydroxy-2-nonenal 14, coriolic and tetranorcoriolic acid methyl esters 28 and 31, trienals 39 or 40, and the 12-hydroxy-5,8,10 heptadecatrienoic ester 41.Some of them have been tested as part of a program dealing with the interaction of blood platelets and eicosanoids; it gave new results concerning the influence of the absolute configuration at the carbon bearing the hydroxyl group and the stereochemistry of the diene.