118943-00-3

Basic information

• Product Name: 1-acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-amino-1,2-dideoxy-D-glucitol
• Synonyms: 1-acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-amino-1,2-dideoxy-D-glucitol
• CAS NO: 118943-00-3
• Molecular Weight: 425.436
• Mol File: 118943-00-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-amino-1,2-dideoxy-D-glucitol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-amino-1,2-dideoxy-D-glucitol(118943-00-3)
• EPA Substance Registry System: 1-acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-amino-1,2-dideoxy-D-glucitol(118943-00-3)

Safety Data

• Hazardous Substances Data: 118943-00-3(Hazardous Substances Data)

Upstream product

• 29625-73-8 2-acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-1-N-(4-L-aspartoyl)-2-deoxy-β-D-glucopyranosylamine 

Relevant articles and documents

A METHOD FOR REDUCTIVE CLEAVAGE OF N-GLYCOSYLAMIDE CARBOHYDRATE-PEPTIDE BOND

A new, mild method for the splitting of N-linked oligosaccharides from glycoproteins includes treatment of glycoproteins (ovomucoid, flavoprotein, ribonuclease B, hemagglutinin, or transferrin) with 2 M LiBH4 in 25 mM LiOH - 50 mM Li citrate - 70percent aqueous tert-butyl alcohol (5 h, 45 deg C), followed by hydrolysis of the resulting glycosylamine with aqueous acetic acid.The oligosaccharides formed were easily isolated by gel filtration and cation-exchange chromatography in 60-80 percent yields.The reaction was accompanied by the intense reductive cleavage of peptide bonds with formation of amino alcohols, but N-deacetylation of hexosamine was completely excluded.The optimal conditions of this reaction were chosen by use of a model glycopeptide, 2-acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-1-N-(4-L-aspartoyl)-2-deoxy-β-D-glucopyranosylamine