118966-00-0

Basic information

• Product Name: (2S,3S)-3-Cyclohexyl-2-dibenzylamino-3-hydroxy-propionic acid
• CAS NO: 118966-00-0
• Molecular Weight: 367.488
• Mol File: 118966-00-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,3S)-3-Cyclohexyl-2-dibenzylamino-3-hydroxy-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-3-Cyclohexyl-2-dibenzylamino-3-hydroxy-propionic acid(118966-00-0)
• EPA Substance Registry System: (2S,3S)-3-Cyclohexyl-2-dibenzylamino-3-hydroxy-propionic acid(118966-00-0)

Safety Data

• Hazardous Substances Data: 118966-00-0(Hazardous Substances Data)

Upstream product

• 2719-27-9 cyclohexanylcarbonyl chloride 
• 94226-84-3 3-Cyclohexyl-2-dibenzylamino-3-oxo-propionic acid tert-butyl ester 
• 94226-83-2 3-Cyclohexyl-2-dibenzylamino-3-oxo-propionic acid methyl ester 
• 94226-56-9 tert-butyl 2-(dibenzylamino)ethanoate 
• 94226-55-8 (dibenzylamino)acetic acid methyl ester 
• 17360-47-3 N,N-dibenzylglycine 
• 94226-71-8 (2S,3S)-3-Cyclohexyl-2-dibenzylamino-3-hydroxy-propionic acid tert-butyl ester 
• 118965-95-0 (Z)-tert-butoxy-2-(dibenzylamino)-1-(trimethylsiloxy)ethylene 
• 94226-71-8 (2S,3R)-3-Cyclohexyl-2-dibenzylamino-3-hydroxy-propionic acid tert-butyl ester 
• 2043-61-0 cyclohexanecarbaldehyde 
• 94226-71-8 3-Cyclohexyl-2-dibenzylamino-3-hydroxy-propionic acid tert-butyl ester 

Downstream Products

• 5962-92-5 D-erythro-2-amino-3-cyclohexyl-3-hydroxypropionic acid 

Relevant articles and documents

DIBENZYLAMINOACETATES AS USEFUL SYNTHETIC EQUIVALENTS OF GLYCINE IN THEi SYNTHESIS OF α-AMINO-β-HYDROXYACIDS

The stereochemical course of three new simple methodologies for the preparation of α-amino-β-hydroxyacids starting from dibenzylaminoacetates as synthetic equivalents of glycine is described.While the aldol-type condensation via lithium enolates gave results highly dependent on the aldehyde employed, producing in some cases diastereoselectivities up to 5:1 for the anti isomers, the acid-catalysed aldol condensation of silyl ketene acetals yielded predominantly syn adducts with selectivities from 5:1 to 32:1.Finally the acylation-reduction procedure gave the best results in terms of yields and stereoselectivities, affording syn isomers with excellent induction ( 13:1).