119062-06-5

Basic information

• Product Name: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(((S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)amino)-4-oxobutanoic acid
• Synonyms: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(((S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)amino)-4-oxobutanoic acid
• CAS NO: 119062-06-5
• Molecular Weight: 532.55
• Mol File: 119062-06-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(((S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)amino)-4-oxobutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(((S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)amino)-4-oxobutanoic acid(119062-06-5)
• EPA Substance Registry System: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(((S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)amino)-4-oxobutanoic acid(119062-06-5)

Safety Data

• Hazardous Substances Data: 119062-06-5(Hazardous Substances Data)

Upstream product

• 3417-91-2 L-tyrosine methyl ester HCl 
• 71989-14-5 Fmoc-(tBu)Asp-OH 
• 60-18-4 L-tyrosine 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 136083-57-3 N-α-9-fluorenylmethoxycarbonyl-aspartic acid 

Downstream Products

• 119062-07-6 Fmoc-Asp-Tyr-OH 

Relevant articles and documents

Tyrosine-Specific Modification via a Dearomatization-Rearomatization Strategy: Access to Azobenzene Functionalized Peptides

Azobenzene functionalized peptides are of great importance in photoresponsive biosystems and photopharmacology. Herein, we report an efficient approach to prepare azobenzene functionalized peptides through late-stage modification of tyrosine-containing peptides using a dearomatization-rearomatization strategy. This approach shows good chemoselectivity and site selectivity as well as sensitive group tolerance to various peptides. This method enriches the postsynthetic modification toolbox of peptides and has great potential to be applied in medicinal chemistry and chemical biology.

Enzymatic synthesis of cholecystokinin-octapeptide

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