1190921-72-2Relevant articles and documents
Studies towards topical selective β2-adrenoceptor agonists with a long duration of action
Bouyssou, Thierry,Rudolf, Klaus,Hoenke, Christoph,Lustenberger, Philipp,Schnapp, Andreas,Konetzki, Ingo
scheme or table, p. 5237 - 5240 (2010/03/31)
β2-Adrenoceptor agonists with basic and acidic groups attached via an alkyl linker to the phenyl ethanolamine core were prepared and investigated in vitro and in vivo. The compounds exhibited a high potency in a functional cellular assay and a bronchoprotective effect in a guinea pig model which lasted over the complete study period of 5 h.