1190927-74-2

Basic information

• Product Name: 2,4-DICHLORO-6,7-DIHYDRO-5H-PYRROLO[3,4-D]PYRIMIDINEHYDROCHLORIDE
• Synonyms: 2,4-Dichloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyriMidine HCl;2,4-dichloro-5H,6H,7H-pyrrolo[3,4-d]pyrimidine hydrochloride;2,4-DICHLORO-6,7-DIHYDRO-5H-PYRROLO[3,4-D]PYRIMIDINEHYDROCHLORIDE
• CAS NO: 1190927-74-2
• Molecular Formula: C₆H₅Cl₂N₃*ClH
• Molecular Weight: 226
• Product Categories: pyrimidine;Heterocycle-Pyrimidine series
• Mol File: 1190927-74-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,4-DICHLORO-6,7-DIHYDRO-5H-PYRROLO[3,4-D]PYRIMIDINEHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DICHLORO-6,7-DIHYDRO-5H-PYRROLO[3,4-D]PYRIMIDINEHYDROCHLORIDE(1190927-74-2)
• EPA Substance Registry System: 2,4-DICHLORO-6,7-DIHYDRO-5H-PYRROLO[3,4-D]PYRIMIDINEHYDROCHLORIDE(1190927-74-2)

Safety Data

• Hazardous Substances Data: 1190927-74-2(Hazardous Substances Data)

Usage

General Description

2,4-DICHLORO-6,7-DIHYDRO-5H-PYRROLO[3,4-D]PYRIMIDINEHYDROCHLORIDE is a chemical compound with the molecular formula C5H4Cl2N4. It is a hydrochloride salt form of the organic compound 2,4-dichloro-6,7-dihydro-5H-pyrrolo[3,4-D]pyrimidine, which belongs to the group of pyrrolopyrimidine analogs. 2,4-DICHLORO-6,7-DIHYDRO-5H-PYRROLO[3,4-D]PYRIMIDINEHYDROCHLORIDE is commonly used as a pesticide, herbicide, and plant growth regulator. It works by disrupting the growth of unwanted plants and is primarily used in agriculture to control broadleaf weeds in grasses and cereals. 2,4-DICHLORO-6,7-DIHYDRO-5H-PYRROLO[3,4-D]PYRIMIDINEHYDROCHLORIDE is known for its selective toxicity towards plants and is considered to be relatively safe for humans and animals when used according to label instructions.

Upstream product

• 903129-71-5 tert-butyl 2,4-dichloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate 
• 635698-34-9 6-benzyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine-2,4(1H,3H)-dione 

Downstream Products

• 903129-71-5 tert-butyl 2,4-dichloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate 

Relevant articles and documents

Pyrrolidine [3,4-d] pyrimidine derivatives, preparation method and its application

The invention discloses a pyrrolidine[3,4-d]pyrimidine derivative and a preparation method and an application thereof. The pyrrolidine[3,4-d]pyrimidine derivative is an inhibitor of a type I insulin-like growth factor receptor (IGF-1R), and has a good IGF-1R inhibiting function and a good cancer cell proliferation inhibiting function, so that the pyrrolidine[3,4-d]pyrimidine derivative can be taken as a therapeutic agent for treating tumors and relevant diseases.

BICYCLIC PYRIMIDINE DERIVATIVES

[wherein m and n may be the same or different and each represents an integer of 1 to 3 wherein m + n is 4 or less; R1 represents NR4R5 (wherein R4 and R5 may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl or the like); R2 represents the above Formula (II), Formula (IV) or the like; A represents a single bond, -C(=O)-, -SO2-, -OC(=O)- or the like; and R3 represents substituted or unsubstituted lower alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aralkyl or the like]ψBicyclic pyrimidine derivatives represented by the above Formula (I), or quaternary ammonium salts thereof, or pharmaceutically acceptable salts thereof, or the like, are provided. These have anti-inflammatory activities or modulation activities on the functions of TARC and/or MDC and are useful for treating and/or preventing a disease which is related to T cells, such as an allergic disease, an autoimmune disease or transplant rejection.