1191099-97-4Relevant articles and documents
Potent and selective steroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone
Bellavance, Edith,Luu-The, Van,Poirier, Donald
experimental part, p. 7488 - 7502 (2010/06/13)
17β-Hydroxysteroid dehydrogenase type 7 (17β-HSD7) catalyzes the reduction of estrone (E1) into estradiol (E2) and of dihydrotestosterone (DHT) into 5α-androstane-3β,17β-diol (3β-diol), therefore modulating the level of mitogenic est