119168-77-3 Usage
Description
4-Chloro-N-(4-tert-butylbenzyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide is a chemical compound belonging to the class of pyrazole carboxamides. It is characterized by its solid-state appearance and is known for its acaricidal and insecticidal properties, making it a valuable compound in the agricultural and pest control industries.
Uses
Used in Agricultural Industry:
4-Chloro-N-(4-tert-butylbenzyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide is used as an acaricide for controlling and eliminating mites and other small arthropods that are harmful to crops. Its effectiveness in targeting these pests helps to protect plants and increase agricultural yields.
Used in Pest Control:
In the pest control industry, 4-Chloro-N-(4-tert-butylbenzyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide is used as an insecticide to manage and reduce insect populations that can cause damage to various environments, including residential, commercial, and industrial settings.
Used in Commercial Greenhouses:
4-Chloro-N-(4-tert-butylbenzyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide is also utilized in commercial greenhouses as a means to protect valuable plant species from infestations of mites and insects. Its application in this context helps maintain the health and quality of the plants being grown, ensuring a consistent supply of high-quality produce for consumers.
Chemical Properties:
The compound is described as a tan solid, which indicates its physical appearance and state at room temperature. This characteristic is important for its formulation and application methods in various industries.
Metabolic pathway
By incubation of tebufenpyrad with rat liver
homogenate, tebufenpyrad undergoes
biotransformation to yield the major metabolites N-(4-
tert-butylbenzyl)-4-chloro-3-(1-hydroxyethyl)-1-
methylpyrazole-5-carboxamide via hydroxylation of the
w-1-carbon of the ethyl group and N-[4-(1-carboxy-1-
methylethyl)benzyl]-4-chloro-3-ethyl-1-methylpyrazole-
5-carboxamide via oxidation of the methyl group in the
tert-butyl moiety to the carboxylic acid derivatives.When the rat is orally dosed tebufenpyrad, the major
metabolism pathway is via both hydroxylation and
oxidation reactions to yield N-[4-(1-carboxy-1-
methylethyl)benzyl]-4-chloro-3-(1-hydroxyethyl)-1-
methylpyrazole-5-carboxamide which is mainly
excreted in the urine.
Check Digit Verification of cas no
The CAS Registry Mumber 119168-77-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,1,6 and 8 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 119168-77:
(8*1)+(7*1)+(6*9)+(5*1)+(4*6)+(3*8)+(2*7)+(1*7)=143
143 % 10 = 3
So 119168-77-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)
119168-77-3Relevant articles and documents
Method for preparing pyrazole amide compounds by using microreactor
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Paragraph 0073-0083, (2020/07/02)
The invention relates to a method for preparing pyrazole amide compounds by using a microreactor. Specifically, a solution obtained by dissolving a compound shown in a formula (A) in an organic solvent and a solution obtained by dissolving a compound shown in a formula (B) in an organic solvent are mixed through a micro-mixer and then input into a micro-channel reactor for reaction, and a reactionsolution is subjected to aftertreatment to prepare the pyrazole amide compound shown in a formula (C). According to the technical scheme, the micro-channel reactor is adopted, so that the mass transfer and heat transfer efficiency is effectively improved, the reaction rate can be effectively increased, the reaction time is greatly shortened, and the production efficiency is improved; continuous production operation can be achieved, the product quality stability is improved, the equipment integration degree is high, and the occupied space can be reduced; an acid-binding agent does not need tobe additionally added, product aftertreatment is simple, no waste salt is generated, and the product is high in yield, high in purity, safe and environmentally friendly.
Synthesis of fully substituted pyrazoles via regio- and chemoselective metalations
Despotopoulou, Christina,Klier, Lydia,Knochel, Paul
supporting information; experimental part, p. 3326 - 3329 (2009/12/01)
The full functionalization of the pyrazole ring was achieved by successive regioselective metalations using TMPMgCI-LiCI and TMP2Mg.2LiCI. Trapping with various electrophiles led to trisubstituted pyrazoles. An application to the synthesis of the acaricide Tebufenpyrad is reported.
Stabilized agchemical concentrate and use thereof
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, (2008/06/13)
The present invention relates to the stabilization of an agricultural chemical concentrate in aqueous solution and the stabilized concentrate which comprises: (a) between about 0.1 and about 20 wt. % of a stabilizer composition comprising: (1) between about 10 and about 90 wt. % of a water-insoluble, non-crosslinked, film forming polymer, and (2) a polymer solubilizing amount of an aromatic petroleum distillate or an oxygen-containing solvent of an N-alkyl pyrrolidone, a C3 to C8 alkanol, a dibasic acid lower alkyl ester, an ether having a boiling point above 150° C. or mixtures thereof and (b) between about 80 and about 99.9 wt. % concentrate containing a water-insoluble active agricultural chemical, a solvent for said agricultural chemical and a surfactant for said concentrate. The invention also relates to the use of said stabilized concentrate.
