119225-99-9

Basic information

• Product Name: 1-phenyl-2-((2Z)-1,2,3,4-tetrahydroquinolin-2-ylidene)ethan-1-one
• Synonyms: 1-phenyl-2-((2Z)-1,2,3,4-tetrahydroquinolin-2-ylidene)ethan-1-one
• CAS NO: 119225-99-9
• Molecular Weight: 249.312
• Mol File: 119225-99-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-phenyl-2-((2Z)-1,2,3,4-tetrahydroquinolin-2-ylidene)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-2-((2Z)-1,2,3,4-tetrahydroquinolin-2-ylidene)ethan-1-one(119225-99-9)
• EPA Substance Registry System: 1-phenyl-2-((2Z)-1,2,3,4-tetrahydroquinolin-2-ylidene)ethan-1-one(119225-99-9)

Safety Data

• Hazardous Substances Data: 119225-99-9(Hazardous Substances Data)

Upstream product

• 101126-37-8 (Z)-1,2-dihydro-2-benzoylmethylenequinoline 
• 119388-44-2 (Z)-1-phenyl-2-(quinolin-2-yl)ethenol 
• 74124-86-0 3-chlorophenylpropionic acid methyl ester 
• 66191-86-4 3-(2-bromophenyl)propanoic acid,methyl ester 
• 1643-28-3 3-(2-chlorophenyl)propanoic acid 
• 15115-58-9 3-(2-bromophenyl)propionic acid 
• 58380-12-4 <(2-bromophenyl)methyl>propanedicarboxylic acid 
• 1160998-28-6 2-(2-bromo-benzylidene)-malonic acid dimethyl ester 
• 89-98-5 2-chloro-benzaldehyde 
• 1531-38-0 2-benzoylmethylquinoline 
• 91-63-4 2-methylquinoline 

Downstream Products

• 1139921-98-4 (R)-2-(1,2,3,4-tetrahydroquinolin-2-yl)-1-phenylethanone 

Relevant articles and documents

An intramolecular C-N cross-coupling of β-enaminones: A simple and efficient way to precursors of some alkaloids of Galipea officinalis

2-Aroylmethylidene-1,2,3,4-tetrahydroquinolines with the appropriate substituents can be suitable precursors for the synthesis of alkaloids from Galipea officinalis (cuspareine, galipeine, galipinine, angustureine). However, only two, rather low-yielding procedures for their synthesis are described in the literature. We have developed a simple and efficient protocol for an intramolecular, palladium or copper-catalysed amination of both chloro- and bromo-substituted 3-amino-1,5-diphenylpent-2-en-1-ones leading to the above-mentioned tetrahydroquinoline moiety. The methodology is superior to the methods published to date.

Highly enantioselective iridium-Catalyzed hydrogenation of 2-Benzylquinolines and 2-Functionalized and 2,3-disubstituted quinolines

The enantioselective hydrogenation of 2-benzylquinolines and 2-functionalized and 2,3-disubstituted quinohnes was developed by using the [Ir(COD)Cl]2/bisphosphine/I2 system with up to 96% ee. Moreover, mechanistic studies revealed the hydrogenation mechanism of quinoline involves a 1,4-hydride addition, isomerization, and 1,2-hydride addition, and the catalytic active species may be a Ir(III) complex with chloride and iodide.